Research ArticleOpen AccessGoogle Scholar indexed

Biliary Tract Pathologies: Epidemiological, Clinical and Paraclinical Aspects in N’Djamena

¹ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
² Service d’Imagerie Médicale du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
³ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
⁴ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
⁵ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
⁶ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
⁷ Service de Gastroentérologie du Centre Hospitalier Universitaire la Renaissance, N’Djamena, Chad
⁸ Service de Gastroentérologie du Centre Hospitalier Universitaire la Renaissance, N’Djamena, Chad
⁹ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
¹⁰ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
¹¹ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad
¹² Service de Gastroentérologie du Centre Hospitalier Universitaire la Renaissance, N’Djamena, Chad
¹³ Service de Gastroentérologie/Médecine Interne du Centre Hospitalier Universitaire la Référence Nationale, N’Djamena, Chad

Open Journal of Gastroenterology·Volume 16 (2026)·Pages 123–128·Published 12 March 2026·DOI10.4236/ojgas.2026.163013

Abstract

Introduc tion: Biliary tract pathologies are a frequent reason for consultation and hospitalization in gastroenterology and digestive surgery, with a significant impact on the health system, particularly in hospital settings in Chad. The aim of this study is to evaluate the epidemiological, clinical and paraclinical characteristics of the main biliary tract pathologies encountered at the National Reference University Hospital of N’Djamena. Patients and Methods: This was a descriptive retro-prospective study conducted over 5 years among patients aged 18 years and older hospitalized for biliary tract diseases in the Department of Internal Medicine/Gastroenterology. Socio-demographic, clinical and paraclinical data were collected from usable medical records, entered into Excel and analyzed using SPSS 18.0. Results: Of 3365 hospitalized patients, 202 met the inclusion criteria, corresponding to a hospital prevalence of 6%. The mean age was 55 years, with a female predominance (63.36%) and a sex ratio of 0.57. The main symptoms were vomiting (85.14%) and abdominal pain (78.21%). Hyperbilirubinemia was found in 80.2% of cases. Abdominal ultrasound revealed a predominance of gallstone disease (51%), while abdominal CT scan identified gallbladder tumors in 2.4% of cases. Conclusion: In our context, biliary tract pathologies are dominated by gallstone disease, with a clear female predominance.

KeywordsBiliary Tract PathologiesEpidemiologyClinicalParaclinicalN&#8217DjamenaChad

Hamza, S., Phelip, J. and Lepage, C. (2012) Épidémiologie des cancers des voies biliaires. Cancéro Digest , 4, 22-25. https://doi.org/10.4267/2042/45921
Ka, I., Faye, M., Diop, P.S., Niang, A.B., Ndoye, J.M. and Fall, B. (2018) Cancers Biliaires: aspects épidémiologiques cliniques et thérapeutiques à propos de 20 cas. Pan African Medical Journal , 29, Article 13. https://doi.org/10.11604/pamj.2018.29.13.9922
Payen, J., Muscari, F., Vibert, É., Ernst, O. and Pelletier, G. (2011) Lithiase Biliaire. La Presse Médicale , 40, 567-580. https://doi.org/10.1016/j.lpm.2011.01.024
Tracey, J.Y. and Moossa, A.R. (2006) Surgical Treatment of Benign Lesions and Strictures of Bile Ducts. Der Chirurg , 77, 315-324.
Baron, T.H. (2007) Natural Orifice Transluminal Endoscopic Surgery. British Journal of Surgery , 94, 1-2. https://doi.org/10.1002/bjs.5681
Sacko, O., Diallo, S., Soumaré, L., e t al . (2007) The Lithiasis of Choledoque: Epidemiological Aspects, Clinics and Therapeutiques in the Surgery Department “A” at the University Hospital Point G. Médecine d ’ Afrique Noire , 54, 104-109.
Mehinto, D.K., Adegnika, A.B. and Padonou, N. (2006) Lithiase biliaire en chirurgie viscérale au Centre National Hospitalier et Universitaire Hubert Koutoucou Maga (CNHU-HKM) de Cotonou. Médecine d ’ Afrique Noire , 53, 497-500.
Owono, P., Mingoutaud, L., Ivala, L., et al . (2008) Cholécystectomie par laparoscopie. Expérience du centre hospitalier de Libreville, à propos de 25 cas. Médecine d ’ Afrique Noire , 55, 286-292.
Bouvier, A.M., Remontet, L., Jougla, E., Launoy, G., Grosclaude, P., Buémi, A., et al . (2004) Incidence of Gastrointestinal Cancers in France. Gastroentérologie Clinique et Biologique , 28, 877-881. https://doi.org/10.1016/s0399-8320(04)95152-4
Khan, S.A., Thomas, H.C., Davidson, B.R. and Taylor-Robinson, S.D. (2005) Cholangiocarcinoma. The Lancet , 366, 1303-1314. https://doi.org/10.1016/s0140-6736(05)67530-7
Shaib, Y.H., El-Serag, H.B., Davila, J.A., Morgan, R. and McGlynn, K.A. (2005) Risk Factors of Intrahepatic Cholangiocarcinoma in the United States: A Case-Control Study. Gastroenterology , 128, 620-626. https://doi.org/10.1053/j.gastro.2004.12.048
Malhi, H. and Gores, G.J. (2006) Cholangiocarcinoma: Modern Advances in Understanding a Deadly Old Disease. Journal of Hepatology , 45, 856-867. https://doi.org/10.1016/j.jhep.2006.09.001

Menu

Biliary Tract Pathologies: Epidemiological, Clinical and Paraclinical Aspects in N’Djamena

Abstract

References (18)