HCV infection in children is different from the adult infection in many ways like natural course of the disease; duration, therapeutic response and side effects profile of the drug therapy; and prognosis. Special considerations include what is the appropriate time to investigate a suspected child, when to institute and choice of drug therapy and how to prevent vertical transmission. In this article, based on the current evidence suggested guidelines for the diagnosis and management of chronic HCV infection in children is given. Feedback to help improve/modify these recommendations by those experienced in dealing with the children will be welcome.
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