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When the skin meets the bowel: About a case
Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Anatomic Pathology Institute, Department of Neurosciences, Polytechnic University of Marche, Ancona, Italy
Anatomic Pathology Institute, Department of Neurosciences, Polytechnic University of Marche, Ancona, Italy
Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 1 Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 2 Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 3 Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 4 Anatomic Pathology Institute, Department of Neurosciences, Polytechnic University of Marche, Ancona, Italy
- 5 Anatomic Pathology Institute, Department of Neurosciences, Polytechnic University of Marche, Ancona, Italy
- 6 Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 7 Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
- 8 Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy
Open Journal of Gastroenterology·Volume 03 (2013)·Pages 303–306·Published 15 October 2013·DOI10.4236/ojgas.2013.36052
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Abstract
Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal region which may be complicated by extraintestinal manifestations, as cutaneous involvement. Immune dysregulation resulting in a lymphocyte mediated destructive process has been suggested as a possible pathogenetic link between gut and skin-related manifestations. The authors describe an atypical clinical aspect of lichen ruber planus in a patient affected by vitiligo, alopecia areata and ulcerative colitis.
KeywordsUlcerative ColitisVitiligoLichen Ruber PlanusAlopecia AreataAutoimmunity
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