Analysis on the clinical and endoscopic parameters in 1247 patients with reflux esophagitis

Abstract

Aim: To summarize and analyze the clinical and endoscopic parameters in patients with reflux esophagitis(RE). Methods ： 1247 patients with RE were diagnosed in our hospital endoscopy center from September 2010 to August 2012 . The general information of the patients and the relationship between endoscopic classification and concomitant diseases were analyzed. Results : According to the endoscopic findings, 1247 subjects (4.70 %) were found to have RE ： 932 (74.74%) males and 315 (25.26%) females, and the male to female ratio was 2.96:1. The peak age of prevalence was 50 to 59 (27.35%) which is followed by 40 to 49 (23.10%). In this study, most of the patients had a mild degree of esophagitis representing LA-A in 60.63% and LA-B in 34.24%. The antrum hyperemia was found in 291 patients with esophagitis (23.34%), followed by antrum erosion (20.13%) and hatal hernia (15.88%). There is no statistically significant relevance between Helicobacter pylori infection and RE (P > 0.05), but Barrett’s esophagus, duodenal ulcer , gastroesophageal tumors, a history of gastroesophageal surgery and antrum hyperemia were found to be associated with RE (P < 0.05) . Conclusion: The prevalence rate of endoscopic RE in our study was 4.70%, and most patients had a mild grade esophagitis. Male, advanced age, Barrett’s esophagus, duodenal ulcer, gastroesophageal tumors and a history of gastroesophageal surgery are the risk factors of esophagitis. Antrum hyperemia may reduce the severity of RE.