Clinical and Etiological Profile of Ascites in the Departmental University Hospital of Porto-Novo
- 1 Hepato-Gastroenterology Department, HKM University Hospital, Cotonou, Benin
- 2 Internal Medicine Department, Departmental University Hospital, Porto-Novo, Benin
- 3 Hepato-Gastroenterology Department, HKM University Hospital, Cotonou, Benin
- 4 Internal Medicine Department, HKM University Hospital, Cotonou, Benin
- 5 Internal Medicine Department, Departmental University Hospital, Porto-Novo, Benin
- 6 Internal Medicine Department, Departmental University Hospital, Porto-Novo, Benin
- 7 Internal Medicine Department, Departmental University Hospital, Porto-Novo, Benin
- 8 Internal Medicine Department, HKM University Hospital, Cotonou, Benin
- 9 Internal Medicine Department, Departmental University Hospital, Porto-Novo, Benin
- 10 Internal Medicine Department, HKM University Hospital, Cotonou, Benin
- 11 Internal Medicine Department, HKM University Hospital, Cotonou, Benin
Abstract
Aim: To determine the frequency, the clinical and etiological aspects of ascites in the Internal Medicine Division of the University Hospital of Porto-Novo. Methods: It was a cross-sectional study with a descriptive focus covering the period from January 16 to August 31, 2015. It covered patients hospitalized for ascites in Internal Medicine Department at the Departmental University Hospital of Porto-Novo during the study period. Data were collected on a survey sheet and entered by Excel and analyzed with SPSS. The Chisquare test was used for statistical analysis and a significance threshold of 5% was retained. Results: Of the 511 hospitalized patients during the study period, 61 (11.9%) had ascites. The mean age was 49.6 ± 13.6 years with extremes of 19 years and 80 years. There was a male predominance with a sex ratio of 2.05. Ascites were often type III (34 patients, 55.7%), or type II (22 patients, 36.1%). The frequent signs were hepatomegaly (65.6%), splenomegaly (45.9%), pelvic limb edema (44.3%), and abdominal collateral venous circulation (39.3%). The macroscopic appearance of the ascites fluid was dominated by citrin yellow (82%), followed by hazy (11.5%). The hematic appearance was found in 6.5% of the cases. Hepatic cirrhosis was the most frequent etiology (34.4%) followed by overall heart failure (21.0%). Hepatocellular carcinoma was found in 16% of cases and nephrotic syndrome in 10% of cases. Conclusion: The etiological diversity of ascites, found in our study, imposes a careful clinical and paraclinical approach.
- Soren, M., Jens, H. and Flemming, B. (2009) Ascites: Pathogenesis and Therapeutic Principles. Scandinavian Journal of Gastroenterology, 44, 902-911. https://doi.org/10.1080/00365520902912555
- Moore, C.M. and Van Thiel, D.H. (2013) Cirrhotic Ascites Review: Pathophysiology, Diagnosis and Management. World Journal of Hepatology, 5, 251-263. https://doi.org/10.4254/wjh.v5.i5.251
- European Association for the Study of the Liver (2010) Clinical Practice Guidelines on the Management of Ascites, Spontaneous Bacterial Peritonitis, and Hepatorenal Syndrome in Cirrhosis. Journal of Hepatology, 53, 397-417. https://doi.org/10.1016/j.jhep.2010.05.004
- Pexa-Tittia, E., Raisinb, J. and Frenzera, A. (2012) Ascites: Etiologies, Investigations and Treatment. Forum Médical Suisse, 12, 951-954.
- Bresson-Hadni, S. (2000) Diagnostic Guidance and Management in the Presence of Ascites. Lettre de l’Hépato-Gastroentérologue, 3, 189-92.
- Sidibe, A. (2009) Ascites: Clinical Presentation and Aetiological Profile of Ascites in the Department of Hepato-Gastroenterology of CHU Gabriel TOURE. Ph.D. Dissertation, University of Bamako, Bamako.
- Sehonou, J., Kodjoh, N., Sake, K. and Mouala, C. (2010) Hepatic Cirrhosis in Cotonou: Factors Related to Death. Médecine tropicale, 70, 375-78.
- Bambara, M.L. (2013) Epidemiological, Diagnostic, Therapeutic and Evolutionary Aspects of Ascites in the Department of Medicine of the Bobo-Dioulasso University Hospital Center. Ph.D. Dissertation, Higher Institute of Health Sciences, Bobo-Dioulasso.
- Ouattara, B., Kra, O., Kouassi, L., Kone, S., Biekre, R., Toure, K.H., et al. (2014) Aetiologies of Ascites in a Department of Internal Medicine in Côte d’Ivoire. African Journal of Internal Medicine, 3, 56-59.
- Drabo, Y.I., Some, M.L., Kabore, J., Sawadogo, S., Lengani, A., Traore, R. et al. (1996) Morbidity and Mortality in the Internal Medicine Department of the Ouagadougou National Hospital Center over 4 Years. Médecine d’Afrique Noire, 43, 655-659.
- Dembele, Y. (2006) The Etiology of Ascites in the Department of Internal Medicine in the C.H.U of Point G, about 67 Cases. Ph.D. Dissertation, University of Bamako, Bamako.
- Doumbia, K., Diarra, M., Konate, A., Sow, H., Soukho, A., Kalle, A. et al. (2012) Ascites, a Pejorative Complication in Cirrhotic in Tropical Environments. Médecine d’Afrique Noire, 59, 274-278.