Level of Cytokines at Teenagers against the Background of Lambliasis Invasia
- 1 Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medical Science, Novosibirsk, Russia
- 2 Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medical Science, Novosibirsk, Russia
- 3 Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medical Science, Novosibirsk, Russia
- 4 Novosibirski State Medical University of the Ministry of Health of Russia, Moscow, Russia
- 5 Novosibirski State Medical University of the Ministry of Health of Russia, Moscow, Russia
- 6 Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medical Science, Novosibirsk, Russia
Abstract
The cytokines’ levels of pro-inflammatory and anti-inflammatory activity, levels of lactoferrin, of the circulating immune complexes and the level of antibodies to antigens of the native deoxyribonucleic acid (DNA) are investigated. The purpose of investigation was to study the pathogenic features of clinical course of chronic lambliasis invasia at teenagers. The statistically significant hypercitokinemia owing to the pro-inflammatory and anti-inflammatory cytokines with the highest concentration of IL-1β, IL-4, the high level of lactoferrin-protein of acute phase, the occurrence of markers of cellular damage, the high level of immune complexes and the stimulation of humoral link of immune system, the high level of antibodies to the antigen of native DNA, are registered. The obtained data may be used as additional diagnostic criteria of lambliasis invasia at teenagers.
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