Research ArticleOpen AccessGoogle Scholar indexed
Bioinformatics of Profilin in Wheat
School of Life Science, Shanxi Normal University, Linfen, China
Higher Education Key Laboratory of Plant Molecular and Environmental Stress Response, Shanxi Normal University, Linfen, China
School of Life Science, Shanxi Normal University, Linfen, China
School of Life Science, Shanxi Normal University, Linfen, China
- 1 School of Life Science, Shanxi Normal University, Linfen, China
- 2 Higher Education Key Laboratory of Plant Molecular and Environmental Stress Response, Shanxi Normal University, Linfen, China
- 3 School of Life Science, Shanxi Normal University, Linfen, China
- 4 School of Life Science, Shanxi Normal University, Linfen, China
Open Journal of Immunology·Volume 06 (2016)·Pages 181–188·Published 24 November 2016·DOI10.4236/oji.2016.64017
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Abstract
Profilin is a small actin-binding protein that is essential in all organisms. While the wheat genome sequence database is not currently available, the exploration of bioinformatics is very important. Therefore, this article predicted the structure and function of profilin in wheat by bioinformatics methods. The amino acid sequence of profilin was searched in GeneBack. While its signal peptides were analyzed through CBS prediction server, the hydrophobicities were analyzed by bioedit software, we used EMBnet server and DNAstar to analyse the transmembrane domains and the B-cell epitopes of the profilin respectively. Finally, the tertiary structure of the protein was predicted through Swiss-Model. This information will help develop rational strategies to improve the component-resolving diagnosis and immunotherapy of profilin allergy.
KeywordsWheatProfilin AllergicBioinformatics
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