Research ArticleOpen AccessGoogle Scholar indexed
Sea-blue histiocytes syndrome: Case report and review of literature
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 1 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 2 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 3 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 4 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 5 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 6 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
- 7 Department of Internal Medicine, Sahloul Hospital, Soussa, Tunisia
Open Journal of Internal Medicine·Volume 03 (2013)·Pages 19–21·Published 22 March 2013·DOI10.4236/ojim.2013.31005
Copy link · social · email
Abstract
A 57-year-old female was admitted with pancytopenia, and mild splenomegaly. The multiple myeloma diagnosis was wrongly made since the discovery of monoclonal peak to the protein electrophoresis. Further microscopic examination of bone marrow revealed the accumulation of sea-blue histiocytes. The evolution was stable and the patient did not receive any treatment due to the lack of nervous symptoms.
KeywordsSyndrome of the Sea-Blue HistiocytePancytopeniaSplenomegaly
- Etcheverry, R., Daiber, A., Boris, E. and Durán, N. (1991) Sea-blue histiocyte syndrome. Revue of Medecine Cheldren, 119, 1008-1015.
- Glew, R.H., Haese, W.H. and McIntyre, P.A. (1973) Myeloid metaplasia with myelofibrosis. The clinical spectrum of extramedullary hematopoiesis and tumor formation. Johns Hopkins Medical Journal, 132, 253-270.
- Pereira, A., Bruguera, M., Cervantes, F. and Rozman, C. (1988) Liver involvement at diagnosis of primary myelofibrosis: A clinicopathological study of twenty-two cases. European Journal of Haematology, 40, 355-361. doi:10.1111/j.1600-0609.1988.tb00191.x
- Howard, M.R. and Kesteven, P.J.L. (1993) Sea blue histiocytosis: A common abnormality of the bone marrow in myelodysplastic syndromes. Journal of Clinical Pathology, 46, 1030-1032. doi:10.1136/jcp.46.11.1030
- Takahashi, K., Terashima, K., Kojima, M., Yoshida, H. and Kimura, H. (1977) Pathological, histochemical and ultrastructural studies on sea-blue histiocytes and Gaucher-like cells in acquired lipidosis occurring in leukemia. Acta Pathology of Japan, 27, 775-797.
- Rywlin, A.M., Hernandez, J.A., Chastain, D.E. and Pardo, V. (1971) Ceroidhistiocytosis of spleen and bone marrow in idiopathic thrombocytopenic purpura (ITP): A contribution to the understanding of the sea-blue histiocyte. Blood, 37, 587-593.
- Lachman, R., Crocker, A., Schulman, J. and Strand, R. (1973) Radiological findings in Niemann-Pick disease. Radiology, 108, 659-664.
- Quattrin, N., De Rosa, L., Quattrin Jr., S. and Cecio, A. (1978) Sea blue histiocytosis: A clinical cytologic and nosographic study on 23 cases. KlinWschr, 56, 17-30. doi:10.1007/BF01476739
- Howard, M.R. and Kesteven, P.J.L. (1993) Sea blue histiocytosis: A common abnormality of the bone marrow in myelodysplastic syndromes. Journal of Clinical Pathology, 46, 1030-1032. doi:10.1136/jcp.46.11.1030
- Rywlin, A.M., Hernandez, J.A., Chastain, D.E. and Pardo, V. (1971) Ceroidhistiocytosis of spleen and bone marrow in idiopathic thrombocytopenic purpura (ITP): A contribution to the understanding of the sea-blue histiocyte. Blood, 37, 587-593.
- Van OudAlblas, B. and van Furth, R. (1979) Origin, kinetics, and characteristics of pulmonary macrophages in the normal steady state. Journal of Experimental Medicine, 149, 1504-1518. doi:10.1084/jem.149.6.1504
- Links, T.P., Karrenbeld, A., Steensma, J.T., et al. (1992) Fatal respiratory failure caused by pulmonary infiltration by pseudo-Gaucher cells. Chest, 101, 265-266. doi:10.1378/chest.101.1.265