Research ArticleOpen AccessGoogle Scholar indexed
A rare complication of a rare disease: Amyloidosis in situs inversus
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 1 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 2 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 3 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 4 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 5 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 6 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 7 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 8 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 9 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
- 10 Istanbul Medeniyet University, Goztepe Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey
Open Journal of Internal Medicine·Volume 03 (2013)·Pages 55–57·Published 28 May 2013·DOI10.4236/ojim.2013.32013
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Abstract
A 31-year-old female admitted with productive cough and progressively increasing edema in her legs. Four years ago she had the diagnosis of situs inversus (SI) totalis. She had6.5 g/day proteinuria in 24-hour urine analysis. High resolution computed tomography revealed bronchiectatic areas in the left lung. In renal biopsy, kongo and amyloid AA antibody positivity was detected in arteriolar walls and mesangial areas. The patient is currently being followed with ramipril and colchicine treatments. Primary ciliary dyskinesia (PCD) and resultant SI totalis are very rare anomalies characterized by the total inversion of all organs and chronic bronchiectasis. There are very few reports on the association of SI totalis with nephrotic syndrome. P atients with SI totalis and chronic bronchiectasis have increased risk of AA amyloidosis and possibly end stage renal disease and thus these patients should be regularly followed with proteinuria and serum creatinine levels.
KeywordsSitus InversusAmyloidosisBronchiectasisNephrotic Syndrome
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