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Gynecomastia in a Rheumatoid Arthritis Patient; a Rare Side Effect of Methotrexate Therapy
The Indus Hospital, Karachi, Pakistan
The Indus Hospital, Karachi, Pakistan
- 1 The Indus Hospital, Karachi, Pakistan
- 2 The Indus Hospital, Karachi, Pakistan
Open Journal of Internal Medicine·Volume 06 (2016)·Pages 69–71·Published 28 July 2016·DOI10.4236/ojim.2016.63011
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Abstract
We are reporting a case of a 51-year-old male patient with 3-year history of Rheumatoid Arthritis who developed gynecomastia 2 - 3 months after starting Methotrexate (MTX) therapy, without folate supplementation. Two months after stopping MTX therapy and initiating folate supplementation, gynecomastia started resolving. Very few cases of gynecomastia due to MTX therapy have been reported worldwide, although it is a rare yet a significant occurrence and should always be considered in male patients with Rheumatoid Arthritis.
KeywordsRheumatoid ArthritisGynecomastiaMethotrexateFolate
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