Research ArticleOpen AccessGoogle Scholar indexed
Leukocytoclastic Vasculitis Following Ceftriaxone Exposure
Lake Erie College of Osteopathic Medicine, Erie, USA
Lake Erie College of Osteopathic Medicine, Erie, USA
Lake Erie College of Osteopathic Medicine, Erie, USA
Department of Internal Medicine, St Johns’ Riverside Hospital, Yonkers, USA
Department of Hospital Medicine, St. John’s Riverside Hospital, Yonkers, USA
St. John’s Riverside Hospital, Yonkers, USA
- 1 Lake Erie College of Osteopathic Medicine, Erie, USA
- 2 Lake Erie College of Osteopathic Medicine, Erie, USA
- 3 Lake Erie College of Osteopathic Medicine, Erie, USA
- 4 Department of Internal Medicine, St Johns’ Riverside Hospital, Yonkers, USA
- 5 Department of Hospital Medicine, St. John’s Riverside Hospital, Yonkers, USA
- 6 St. John’s Riverside Hospital, Yonkers, USA
Open Journal of Nephrology·Volume 12 (2022)·Pages 222–227·Published 15 April 2022·DOI10.4236/ojneph.2022.122022
Copy link · social · email
Abstract
Leukocytoclastic vasculitis (LCV) is an immune-complex mediated inflammation of dermal capillaries and venules that can occur after infections, drugs, autoimmune disorders, neoplasms, or idiopathically. We present the case of a 59-year-old male who was treated with ceftriaxone for an abscess, S. aureus cellulitis, and osteomyelitis of his right second toe. Biopsy confirmed the diagnosis of LCV and symptoms resolved after ceftriaxone was discontinued and systemic corticosteroids were introduced.
KeywordsLeukocytoclastic VasculitisImmune-ComplexCeftriaxoneLCV
- Einhorn, J. and Levis, J.T. (2015) Dermatologic Diagnosis: Leukocytoclastic Vasculitis. The Permanente Journal, 19, 77-78. https://doi.org/10.7812/TPP/15-001
- Baigrie, D., Goyal, A. and Crane, J.S. (2018) Leukocytoclastic Vasculitis. StatPearls Publishing, Treasure Island.
- Turda, C., Dumnici, O.O. and Huplea, V. (2019) Case Report: Cytomegalovirus Reinfection in a Patient with Chronic Hepatitis C. http://protmed.uoradea.ro/facultate/publicatii/ecotox_zooteh_ind_alim/2019A/Varia/2%20Turda.pdf
- Merkel, P.A. (2021) Overview of and Approach to the Vasculitides in Adults. UpToDate. https://www.uptodate.com/contents/overview-of-and-approach-to-the-vasculitides-in-adults
- Sunderkötter, C., Bonsmann, G., Sindrilaru, A. and Luger, T. (2005) Management of Leukocytoclastic Vasculitis. Journal of Dermatological Treatment, 16,193-206. https://doi.org/10.1080/09546630500277971
- Baigrie, D., Goyal, A. and Crane, J.S. (2021) Leukocytoclastic Vasculitis. StatPearls Publishing, Treasure Island.
- Haehn, D.A., Patel, A., Youngberg, G. and Gonzalez-Estrada, A. (2019) Ceftriaxone-Induced Leucocytoclastic Vasculitis. BMJ Case Reports, 12, e229411. https://doi.org/10.1136/bcr-2019-229411
- Jansen, J.W., Linneman, T.W., Tan, X. and Moenster, R.P. (2019) Comparison of Adverse Drug Reactions between Patients Treated with Ceftaroline or Ceftriaxone: A Single-Center, Matched Cohort Study. Open Forum Infectious Diseases, 6, ofz279. https://doi.org/10.1093/ofid/ofz279
- Ceftriaxone and Leukocytoclastic Vasculitis, a Phase IV … eHealthMe. https://www.ehealthme.com/ds/ceftriaxone/leukocytoclastic-vasculitis/