COVID-19 Infection and Acute Kidney Injury: About 43 Cases Report Collected at the Nephrology Department of the Farah Polyclinic in Abidjan — Oak Academic Publishing
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COVID-19 Infection and Acute Kidney Injury: About 43 Cases Report Collected at the Nephrology Department of the Farah Polyclinic in Abidjan
Farah Polyclinic, Abidjan, Cote d’Ivoire
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Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
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Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
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Farah Polyclinic, Abidjan, Cote d’Ivoire
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Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
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Nephrology Department, Teaching Hospital of Kara, Lome, Togo
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Nephrology and Hemodialysis Department, Teaching Hospital of Sylvanus Olympio, Lome, Togo
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Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
1 Farah Polyclinic, Abidjan, Cote d’Ivoire
2 Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
3 Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
4 Farah Polyclinic, Abidjan, Cote d’Ivoire
5 Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
6 Nephrology Department, Teaching Hospital of Kara, Lome, Togo
7 Nephrology and Hemodialysis Department, Teaching Hospital of Sylvanus Olympio, Lome, Togo
8 Nephrology Department, Teaching Hospital of Treichville, Treichville, Cote d’Ivoire
Background: Acute kidney injury (AKI) is one of the increasingly described complications of coronavirus infection. Objectives: To identify factors associated with death in patients with acute kidney injury (AKI) during Coronavirus disease (COVID-19) in Abidjan, C?te d’Ivoire. Material and Method: This was a monocentric retrospective analytical study of all patients over 18 years of age with AKI during COVID-19 at the Farah Polyclinic in Abidjan, C?te d’Ivoire. AKI was defined and ranked according to Kidney Disease Improving Global Outcomes (KDIGO) 2012. The data were collected from the medical record and processed using RStudio. Results: Forty-three cases were collected. The average age was 58.5 12 years. The sex ratio (M/F) was 4.4. The main comorbidities were high blood pressure (60.4%) and diabetes (37.2%). AKI was at KDIGO stage 3 in 58%, KDIGO 2 in 21% and KDIGO 1 in 21%. The diagnosis of acute tubular necrosis was retained in 44.2% of patients followed by acute functional kidney injury in 32.6%. Hemodialysis was initiated in 48.8% of cases. The main indication of dialysis was anuria (46.6%). In total, 55.8% of patients died. Factors associated with death were KDIGO stage (p = 0.049), and invasive ventilation (p < 0.001) associated with the risk of death in univariate analysis. Conclusion: Mortality is high in patients with AKI during COVID-19 infection.
KeywordsCoronavirusAcute Kidney InjuryAbidjan2020
Cheng, Y., Luo, R., Wang, K., Zhang, M., Wang, Z., Dong, L., et al. (2020) Kidney Disease Is Associated with In-Hospital Death of Patients with COVID-19. Kidney International, 97, 829-838. https://doi.org/10.1016/j.kint.2020.03.005
Martinot, M., Eyriey, M., Gravier, S., Bonijoly, T., Mohseni-Zadeh, M., Braumeisen, C., et al. (2020) Facteur de risque d’évolution défavorable et manifestations extra-pulmonaires au cours du COVID-19. Médecine et Maladies Infectieuses, 50, S81. https://doi.org/10.1016/j.medmal.2020.06.161
Darriverre, L., Fieux, F. and De La Jonquière, C. (2020) Acute Renal Failure during COVID-19 Epidemic. Le Praticien En Anesthesie Reanimation, 24, 207-211. https://doi.org/10.1016/j.pratan.2020.07.004
Martinez-Rojas, M.A., Vega-Vega, O. and Bobadilla, N.A. (2020) Is the Kidney a Target of SARS-CoV-2? American Journal of Physiology-Renal Physiology, 318, F1454-F1462. https://doi.org/10.1152/ajprenal.00160.2020
Karray, R., Jamoussi, A., Ayed, S., Lakhdhar, D., Rachdi, E, Khelil, J.B., et al. (2020) Surmortalité de l’insuffisance rénale aiguë oligoanurique au cours de la COVID-19: étude prospective tunisienne. Néphrologie & Thérapeutique, 16, 312. https://doi.org/10.1016/j.nephro.2020.07.170
Peleg, Y., Kudose, S., D’Agati, V., Siddall, E., Ahmad, S., Nickolas, T., et al. (2020) Acute Kidney Injury Due to Collapsing Glomerulopathy Following COVID-19 Infection. Kidney International Reports, 5, 940-945. https://doi.org/10.1016/j.ekir.2020.04.017
Cheruiyot, I., Henry, B., Lippi, G., Kipkorir, V., Ngure, B., Munguti, J., et al. (2020) Acute Kidney Injury is Associated with Worse Prognosis in COVID-19 Patients: A Systematic Review and Meta-Analysis. Acta Biomedica: Atenei Parmensis, 91, e2020029.
Eknoyan, G., Lameire, N., Eckardt, K. and Kasiske, B. (2012) Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney International Supplements, 2, 1-138.
Afriyie-Mensah, J., Aboagye, E.T., Ganu, V.J., Bondzi, S., Tetteh, D., Kwarteng, E., et al. (2021) Clinical and Therapeutic Outcomes of COVID-19 Intensive Care Units (ICU) Patients: A Retrospective Study in Ghana. Pan African Medical Journal, 38, Article 107. https://doi.org/10.11604/pamj.2021.38.107.27131
Ketfi, A., Chabati, O., Chemali, S., Mahjoub, M., Gharnaout, M., Touahri, R., et al. (2020) Profil clinique, biologique et radiologique des patients Algériens hospitalisés pour COVID-19: Données préliminaires. Pan African Medical Journal, 35, Article 77. https://doi.org/10.11604/pamj.supp.2020.35.2.23807
Lucana, G.G.A. and Casas, R. (2021) POS-003 Acute Kidney Injury in Critically Ill Patients with COVID-19 Experience of a ICU Bolivian Center Reference. Kidney International Reports, 6, S1-S2. https://doi.org/10.1016/j.ekir.2021.03.009
Gupta, S., Coca, S.G., Chan, L., Melamed, M.L., Brenner, S.K., Hayek, S.S., et al. (2021) AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19. Journal of the American Society of Nephrology, 32, 161-176. https://doi.org/10.1681/ASN.2020060897
Chan, L., Chaudhary, K., Saha, A., Chauhan, K., Vaid, A., Zhao, S., et al. (2021) AKI in Hospitalized Patients with COVID-19. Journal of the American Society of Nephrology, 32, 151-160. https://doi.org/10.1681/ASN.2020050615
Ibrahim, O.R., Oloyede, T., Gbadamosi, H., Musa, Y., Aliu, R., Bello, S.O., et al. (2021) Acute Kidney Injury in COVID-19: A Single—Center Experience in Nigeria. Anaesthesia. Pain & Intensive Care, 25, 470-477.
Rubin, S., Orieux, A., Prevel, R., Carrié, C., Dewitte, A., Camou, F., et al. (2020) Caractérisation de l’insuffisance rénale aiguë chez les patients de réanimation atteints du COVID-19. Néphrologie & Thérapeutique, 16, 247. https://doi.org/10.1016/j.nephro.2020.07.005
Gutiérrez-Abejón, E., Martín-García, D., Tamayo, E., álvarez, F.J. and Herrera-Gómez, F. (2021) Clinical Profile, Pharmacological Treatment, and Predictors of Death among Hospitalized COVID-19 Patients with Acute Kidney Injury: A Population-Based Registry Analysis. Frontiers in Medicine (Lausanne), 8, Article ID: 657977. https://doi.org/10.3389/fmed.2021.657977
Sampathkumar, H.H., Rajiv, A., Kumar, S., Sampathkumar, D., Kumar, S., et al. (2021) Incidence, Risk Factors and Outcome of COVID-19 Associated AKI—A Study from South India. Journal of the Association of Physicians of India, 69, 11-12.
Biswas, M., Rahaman, S., Biswas, T.K., Haque, Z. and Ibrahim, B. (2021) Association of Sex, Age, and comorbidities with mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Intervirology, 64, 36-47. https://doi.org/10.1159/000512592
Rapp, J.L., Lieberman-Cribbin, W., Tuminello, S. and Taioli, E. (2021) Male Sex, Severe Obesity, Older Age, and Chronic Kidney Disease are Associated with COVID-19 Severity and Mortality in New York City. Chest, 159, 112-115. https://doi.org/10.1016/j.chest.2020.08.2065
Maksimowski, N.A., Scholey, J.W. and Williams, V.R. (2021) Network (NEPTUNE) NSS. Sex and Kidney ACE2 Expression in Primary Focal Segmental Glomerulosclerosis: A Neptune Study. PLOS ONE, 16, e0252758. https://doi.org/10.1371/journal.pone.0252758
Yanes Cardozo, L.L., Rezq, S., Pruett, J.E. and Romero, D.G. (2021) Androgens, the kidney, and COVID-19: An Opportunity for Translational Research. American Journal of Physiology-Renal Physiology, 320, F243-F248. https://doi.org/10.1152/ajprenal.00601.2020
Shi, Y., Yu, X., Zhao, H., Wang, H., Zhao, R. and Sheng, J. (2020) Host Susceptibility to Severe COVID-19 and Establishment of a Host Risk Score: Findings of 487 Cases outside Wuhan. Critical Care, 24, Article No. 108. https://doi.org/10.1186/s13054-020-2833-7
Hirsch, J.S., Ng, J.H., Ross, D.W., Sharma, P., Shah, H.H. and Barnett, R.L., et al. (2020) Acute Kidney Injury in Patients Hospitalized with COVID-19. Kidney International, 98, 209-218. https://doi.org/10.1016/j.kint.2020.05.006
Gilbert, R.E., Caldwell, L., Misra, P.S., Chan, K., Burns, K.D., Wrana, J.L., et al. (2020) Overexpression of the SARS-CoV-2 Receptor, ACE-2, in Diabetic Kidney Disease: Implications for Kidney Injury in COVID-19. Canadian Journal of Diabetes, 45, 162-166.
Ritchie, H., Ortiz-Ospina, E., Beltekian, D., Mathieu, E., Hasell, J., Macdonald, B., et al. (2020) Coronavirus Pandemic (COVID-19). Our World in Data. https://ourworldindata.org/covid-vaccinations?country=CIV
Han, S.S., Baek, S.H., Ahn, S.Y., Chin, H.J., Na, K.Y., Chae, D.-W., et al. (2015) Anemia Is a Risk Factor for Acute Kidney Injury and Long-Term Mortality in Critically Ill Patients. The Tohoku Journal of Experimental Medicine, 237, 287-295. https://doi.org/10.1620/tjem.237.287
Benotmane, I., Perrin, P., Gautier-Vargas, G., Bassand, X., Bedo, D., Baldacini, C., et al. (2020) Prédiction de la sévérité de la COVID-19 par les biomarqueurs du syndrome de relargage cytokinique au sein d’une population de transplantés rénaux. Néphrologie & Thérapeutique, 16, 259-260. https://doi.org/10.1016/j.nephro.2020.07.031
Admou, B. (2021) COVID-19 et marqueurs immunologiques pertinents. Pan African Medical Journal, 39, 40. https://doi.org/10.11604/pamj.2021.39.40.23481
Akilesh, S., Nast, C.C., Yamashita, M., Henriksen, K., Charu, V., Troxell, M.L., et al. (2021) Multicenter Clinicopathologic Correlation of Kidney Biopsies Performed in COVID-19 Patients Presenting with Acute Kidney Injury or Proteinuria. American Journal of Kidney Diseases, 77, 82-93. https://doi.org/10.1053/j.ajkd.2020.10.001
Sharma, P., Uppal, N.N., Wanchoo, R., Shah, H.H., Yang, Y., Parikh, R., et al. (2020) COVID-19-Associated Kidney Injury: A Case Series of Kidney Biopsy Findings. Journal of the American Society of Nephrology, 31, 1948-1958. https://doi.org/10.1681/ASN.2020050699
Batlle, D., Soler, M.J., Sparks, M.A., Hiremath, S., South, A.M., Welling, P.A., et al. (2020) Acute Kidney Injury in COVID-19: Emerging Evidence of a Distinct Pathophysiology. Journal of the American Society of Nephrology, 31, 1380-1383. https://doi.org/10.1681/ASN.2020040419
Daou, M. (2021) Evaluation de la pratique de la ventilation mécanique dans le service de réanimation du CHU Gabriel Toure. Thesis, USTTB, Beijing.
Bonny, V., Maillard, A., Mousseaux, C., Plaçais, L. and Richier, Q. (2020) COVID-19: Physiopathologie d’une maladie à plusieurs visages. La Revue de Médecine Interne, 41, 375-389. https://doi.org/10.1016/j.revmed.2020.05.003
Lellou, S., Bouhadda, M., Sahnoun, L., Dali, Y.N. and Bouatam, S. (2021) Place des corticoïdes dans la prise en charge du COVID-19. à propos de 25 cas. Revue des Maladies Respiratoires Actualités, 13, 141. https://doi.org/10.1016/j.rmra.2020.11.297
Alvarez-Garcia, J., Lee, S., Gupta, A., Cagliostro, M., Joshi, A.A., Rivas-Lasarte, M., et al. (2020) Prognostic Impact of Prior Heart Failure in Patients Hospitalized with COVID-19. Journal of the American College of Cardiology, 76, 2334-2348. https://doi.org/10.1016/j.jacc.2020.09.549
Casas-Aparicio, G.A., León-Rodríguez, I., Alvarado De La Barrera, C., González-Navarro, M., Peralta-Prado, A.B., Luna-Villalobos, Y., et al. (2021) Acute Kidney Injury in Patients with Severe COVID-19 in Mexico. PLOS ONE, 16, e0246595. https://doi.org/10.1371/journal.pone.0246595
Alfano, G., Ferrari, A., Fontana, F., Mori, G., Magistroni, R., Meschiari, M., et al. (2021) Incidence, Risk Factors and Outcome of Acute Kidney Injury (AKI) in Patients with COVID-19. Clinical and Experimental Nephrology, 25, 1203-1214. https://doi.org/10.1007/s10157-021-02092-x
Xiao, G.H., Hu, H.B., Wu, F., Sha, T., Zeng, Z.H., Huang, Q.B., et al. (2021) Acute Kidney Injury in Patients Hospitalized with COVID-19 in Wuhan, China: A Single-Center Retrospective Observational Study. Journal of Southern Medical University, 41, 157-163.
Sang, L., Chen, S., Zheng, X., Guan, W., Zhang, Z., Liang, W., et al. (2020) The Incidence, Risk Factors and Prognosis of Acute Kidney Injury in Severe and Critically Ill Patients with COVID-19 in Mainland China: A Retrospective Study. BMC Pulmonary Medicine, 20, Article No. 290. https://doi.org/10.1186/s12890-020-01305-5