Prevalence and Associated Factors of Erectile Dysfunction in Chronic Kidney Disease Patients in Douala, Cameroon
- 1 Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
- 2 Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
- 3 Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon
- 4 Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
- 5 General Hospital of Douala, Douala, Cameroon
- 6 Yaoundé Central Hospital, Yaoundé, Cameroun
Abstract
Background and hypothesis: Chronic kidney disease (CKD) is a major public health concern, with erectile dysfunction (ED) being a common complication that significantly impacts patients’ quality of life. In Cameroon, knowledge regarding the prevalence and associated factors of ED among chronic haemodialysis patients remains limited. The objective of this study was to determine the prevalence and associated factors of erectile dysfunction among chronic haemodialysis patients followed up at the General Hospital of Douala. Method: We conducted a cross-sectional study in the Haemodialysis Unit of the General Hospital of Douala over a 6-month period, recruiting 79 male patients. Erectile dysfunction was assessed using the International Index of Erectile Function (IIEF-5) score. Univariate and multivariate logistic regression analyses were used to identify factors associated with erectile dysfunction. Results: Among the participants, 37% (21) had moderate ED, 37% (21) had mild ED, and 21% (12) had severe ED. Factors associated with ED included diabetes (aOR = 9.7, p = 0.002), stress (aOR = 1.67, p < 0.001), and marital problems (aOR = 1.76, p = 0.01). Conclusion: This study highlights a high prevalence of erectile dysfunction among chronic haemodialysis patients, with associated factors such as diabetes, stress, and marital problems. We recommend that nephrologists systematically screen for erectile dysfunction in these patients and adopt a multidisciplinary management approach, including psychological and urological follow-up as well as rigorous management of comorbidities, to improve their quality of life.
- Levey, A.S. and Coresh, J. (2015) Chronic Kidney Disease. The Lancet , 386, 1564-1574.
- Bikbov, B., Purcell, C.A., Levey, A.S., Smith, M., Abdoli, A., Abebe, M., et al . (2020) Global, Regional, and National Burden of Chronic Kidney Disease, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017. The Lancet , 395, 709-733. https://doi.org/10.1016/s0140-6736(20)30045-3
- Stanifer, J.W., Muiru, A., Jafar, T.H. and Patel, U.D. (2016) Chronic Kidney Disease in Low-and Middle-Income Countries. Nephrology Dialysis Transplantation , 31, 868-874. https://doi.org/10.1093/ndt/gfv466
- Tchouanguep, F.M., Nde, F., Ndam, M., Tchapmi, K., Mbia, L. and Ashuntantang, G. (2020) Chronic Kidney Disease in Cameroon: Prevalence and Associated Factors. BMC Nephrology , 21, 1-9.
- Kaze, F.F., Meto, D.T., Halle, M., Ngogang, J. and Kengne, A. (2015) Prevalence and Determinants of Chronic Kidney Disease in Rural and Urban Cameroonians: A Cross-Sectional Study. BMC Nephrology , 16, Article No. 117. https://doi.org/10.1186/s12882-015-0111-8
- Kengne, A.P. (2008) Heart Failure in Sub-Saharan Africa: A Literature Review with Emphasis on Individuals with Diabetes. Vascular Health and Risk Management , 4, 123-130. https://doi.org/10.2147/vhrm.2008.04.01.123
- Palmer, B.F. (2003) Sexual Dysfunction in Men and Women with Chronic Kidney Disease and End-Stage Kidney Disease. Advances in Renal Replacement Therapy , 10, 48-60. https://doi.org/10.1053/jarr.2003.50003
- Navaneethan, S.D., Vecchio, M., Johnson, D.W., Saglimbene, V., Graziano, G., Pellegrini, F., et al . (2010) Prevalence and Correlates of Self-Reported Sexual Dysfunction in CKD: A Meta-Analysis of Observational Studies. American Journal of Kidney Diseases , 56, 670-685. https://doi.org/10.1053/j.ajkd.2010.06.016
- Rosas, S.E., Joffe, M., Franklin, E., Strom, B.L., Kotzker, W., Brensinger, C., et al . (2001) Prevalence and Determinants of Erectile Dysfunction in Hemodialysis Patients. Kidney International , 59, 2259-2266. https://doi.org/10.1046/j.1523-1755.2001.00742.x
- Foley, R.N. and Collins, A.J. (2013) The USRDS: What You Need to Know About US Dialysis and Transplantation Patients. American Journal of Kidney Diseases , 61, 1-3.
- Halle, M.P., Ashuntantang, G., Kaze, F.F., Takongue, C. and Kengne, A. (2016) Fatal Outcomes among Patients on Maintenance Haemodialysis in Sub-Saharan Africa: A 10-Year Audit from the Douala General Hospital in Cameroon. BMC Nephrology , 17, Article No. 165. https://doi.org/10.1186/s12882-016-0377-5