Status of Healthcare-Associated Infections in Three Nephrology Departments in Dakar: A One-Year Prospective Multicenter Study — Oak Academic Publishing
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Status of Healthcare-Associated Infections in Three Nephrology Departments in Dakar: A One-Year Prospective Multicenter Study
Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
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Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
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Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
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Nephrology Department of the Idrissa Pouye General Hospital, Dakar, Senegal
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Nephrology Department of the Ouakame Military Hospital, Dakar, Senegal
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Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
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Nephrology Department of the Idrissa Pouye General Hospital, Dakar, Senegal
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Cheikh Anta Diop University of Dakar, Dakar, Senegal
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Cheikh Anta Diop University of Dakar, Dakar, Senegal
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Cheikh Anta Diop University of Dakar, Dakar, Senegal
,
Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
1 Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
2 Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
3 Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
4 Nephrology Department of the Idrissa Pouye General Hospital, Dakar, Senegal
5 Nephrology Department of the Ouakame Military Hospital, Dakar, Senegal
6 Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
7 Nephrology Department of the Idrissa Pouye General Hospital, Dakar, Senegal
8 Cheikh Anta Diop University of Dakar, Dakar, Senegal
9 Cheikh Anta Diop University of Dakar, Dakar, Senegal
10 Cheikh Anta Diop University of Dakar, Dakar, Senegal
11 Nephrology Department of Dalaljamm Hospital, Dakar, Senegal
This prospective multicenter descriptive study reports the epidemiological, clinical, microbiological, and outcome profile of healthcare-associated infections (HAIs) in three nephrology departments in Dakar over 12 months. Among 1060 patients seen, 83 HAI cases with microbiological documentation were included, with most events occurring after 7 days of hospitalization and with urinary and hemodialysis catheters as frequent associated devices. Gram-negative bacilli and Staphylococcus spp. predominated, with a high proportion of ESBL and MDR profiles, and outcomes were mainly favorable despite reported mortality.
Fki, H., Yaïch, S., Jdidi, J., Karray, A., Kassis, M. and Damak, J. (2008) Epidemiology of Nosocomial Infections in the University Hospitals of Sfax: Results of the First National Survey of Nosocomial Infection Prevalence. Tunisian Journal of Inctious Diseases , 2, 22-23.
WHO (2026) Les besoins humanitaires en matière de santé dans la Région OMS de la Méditerranée orientale restent les plus élevés au niveau mondial en 2026. http://www.emro.who.int/fr/
European Centre for Disease Prevention and Control: An Agency of the European Union. https://www.ecdc.europa.eu/en/healthcare-associated-infections
Amir, I.J., Zoulati, G., Yahyaoui, G., Mahmoud, M., Chouhan, B.A., Elkbali, N., et al. (2020) Infections Related to Hemodialysis Catheters at Hassan II University Hospital in Fez: Bacterial Ecology and Antibiotic Resistance.
Keita, A.K., Doumbouya, N., Sow, M.S., Konaté, B., Dabo, Y., Panzo, D.A., et al. (2016) Prévalence des infections nosocomiales dans deux hôpitaux de Conakry (Guinée). Santé Publique , 28, 251-255. https://doi.org/10.3917/spub.162.0251
Ka, R. and Al, E. (2024) Aspects bactériologiques des infections liées aux cathéters veineux à l’hôpital Dalal Jamm de Guédiawaye (Sénégal). Revue Malienne d ’ Infectiologie et de Microbiologie , 19, 40-47. https://doi.org/10.53597/remim.v19i3.2890
Abubakar, U., Amir, O. and Rodríguez-Baño, J. (2022) Healthcare-Associated Infections in Africa: A Systematic Review and Meta-Analysis of Point Prevalence Studies. Journal of Pharmaceutical Policy and Practice , 15, Article No. 99. https://doi.org/10.1186/s40545-022-00500-5
Kadiane-Oussou, N.J., Koné, D., Oussou, K.R., Yapo, M.T., Karidioula, J.M., Tiéoulé, S.C., et al. (2023) Prevalence of Nosocomial Infections at the Bouaké University Hospital. Revue africaine d ’ Anesthésiologie et de Médecine d ’ Urgence , 28, 61-65.
Suetens, C., Latour, K., Kärki, T., Ricchizzi, E., Kinross, P., Moro, M.L., et al. (2018) Prevalence of Healthcare-Associated Infections, Estimated Incidence and Composite Antimicrobial Resistance Index in Acute Care Hospitals and Long-Term Care Facilities: Results from Two European Point Prevalence Surveys, 2016 to 2017. Eurosurveillance , 23, Article ID: 1800516. https://doi.org/10.2807/1560-7917.es.2018.23.46.1800516
Morioka, H., Koizumi, Y., Oka, K., Okudaira, M., Tomita, Y., Kojima, Y., et al. (2024) Healthcare-associated Infections in Japanese Hospitals: Results from a Large-Scale Multicenter Point-Prevalence Survey in Aichi, 2020. Infection Control & Hospital Epidemiology , 45, 1263-1270. https://doi.org/10.1017/ice.2024.130
HAIs: Reports and Data. https://www.cdc.gov/healthcare-associated-infections/php/data/index.html
Bwanali, A.N., Lubanga, A.F., Kondowe, S., Nzima, E., Mwale, A., Kamanga, W., et al. (2025) Trends and Patterns of Antimicrobial Resistance among Common Pathogens Isolated from Adult Bloodstream and Urinary Tract Infections in Public Health Facilities in Malawi, 2020-2024. BMC Infectious Diseases , 25, Article No. 946. https://doi.org/10.1186/s12879-025-11335-1
Mendes, R.E., Sader, H.S., Castanheira, M., Flamm, R.K. (2018) Distribution of Main Gram-Positive Pathogens Causing Bloodstream Infections in United States and European Hospitals during the SENTRY Antimicrobial Surveillance Program (2010-2016): Concomitant Analysis of Oritavancin in vitro Activity. Journal of Chemother apy , 30, 280-289. https://doi.org/10.1080/1120009X.2018.1516272
Rha, B., See, I., Dunham, L., Kutty, P.K., Moccia, L., Apata, I.W., et al . (2023) Vital Signs: Health Disparities in Hemodialysis-Associated Staphylococcus aureus Bloodstream Infections—United States, 2017-2020. Morbidity and Mortality Weekly Report , 72, 153-159. https://doi.org/10.15585/mmwr.mm7206e1
Ibitoba, F.A., Akpor, O.A., Ogunkorode, A.O., Bello, A.Y. and Ogunyemi, O.O. (2024) Hemodialysis as a Treatment Option for Chronic Kidney Disease in Ekiti State University Teaching Hospital: A Retrospective Study. KIDNEYS , 13, 48-54. https://doi.org/10.22141/2307-1257.13.1.2024.440
Steinhaus, N., Al-talib, M., Ive, P., Boyles, T., Bamford, C., Davies, M., et al. (2018) The Management and Outcomes of Staphylococcus aureus Bacteraemia at a South African Referral Hospital: A Prospective Observational Study. International Journal of Infectious Diseases , 73, 78-84. https://doi.org/10.1016/j.ijid.2018.06.004
Donkor, E.S., Dayie, N.T.K.D. and Tette, E.M.A. (2019) Methicillin-Resistant staphylococcus aureus in Ghana: Past, Present, and Future. Microbial Drug Resistance , 25, 717-724. https://doi.org/10.1089/mdr.2018.0115
Gagliotti, C., Högberg, L.D., Billström, H., Eckmanns, T., Giske, C.G., Heuer, O.E., et al. (2021) Staphylococcus aureus Bloodstream Infections: Diverging Trends of Meticillin-Resistant and Meticillin-Susceptible Isolates, EU/EEA, 2005 to 2018. Eurosurveillance , 26, Article ID: 2002094. https://doi.org/10.2807/1560-7917.es.2021.26.46.2002094
Mawufemo, T.Y., Dzidzonu, N.K., Déassoua, B.L., Georges, T.K., Badomta, D. and Majesty, W.I. (2020) Bacteriological Profile of Urinary Tract Infections in Chronic Renal Failure Patients Hospitalized in the Nephrology Department. Journal de la recherche scientifique de l ’ Université de Lomé , 22, 237-241.
Oladeinde, B., MSc., M., AIMLS., A., Omoregie, R., MPhil., M., FIMLS., F., et al. (2011) Urinary Tract Infection in a Rural Community of Nigeria. North American Journal of Medical Sciences , 3, 75-77. https://doi.org/10.4297/najms.2011.375
WHO: Surveillance of Antimicrobial Resistance in Europe, 2023 Data. https://www.ecdc.europa.eu/sites/default/files/documents/antimicrobial-resistance-ECDC-WHO-executive-summary-2023-data.pdf
Pilmis, B., Cattoir, V., Lecointe, D., Limelette, A., Grall, I., Mizrahi, A., et al. (2018) Carriage of ESBL-Producing Enterobacteriaceae in French Hospitals: The PORTABLSE Study. Journal of Hospital Infection , 98, 247-252. https://doi.org/10.1016/j.jhin.2017.11.022
Healthcare-Associated Infections Acquired in Intensive Care Units. https://www.ecdc.europa.eu/sites/default/files/documents/healthcare-associated-infections-intensive-care-units-annual-epidemiological-report-2020.pdf
Yahia, A., Ali, M., Zedan, M. and Moemen, D. (2022) Hemodialysis Catheter-Related Infections among Pediatric Patients in Mansoura University Children Hospital. Egyptian Journal of Medical Microbiology , 31, 7-14. https://doi.org/10.21608/ejmm.2022.211924
Keita, O. (2023) Etude des infections urinaires dans le service de médecine au CSRéf de la commune IV du District de Bamako: À propos de 100 cas. https://www.bibliosante.ml/handle/123456789/5964
Epp Sepp, et al. (2019) Phenotypic and Molecular Epidemiology of ESBL-, AmpC-, and Carbapenemase-Producing Escherichia coli in Northern and Eastern Europe. Frontiers in Microbiology , 10, Article 2465. https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2019.02465/full
Wang, T.Z., Kodiyanplakkal, R.P.L. and Calfee, D.P. (2019) Antimicrobial Resistance in Nephrology. Nature Reviews Nephrology , 15, 463-481. https://doi.org/10.1038/s41581-019-0150-7
Mermel, L.A. (2000) Prevention of Intravascular Catheter-Related Infections. Annals of Internal Medicine , 132, 391-402. https://doi.org/10.7326/0003-4819-132-5-200003070-00009
Achieng, W.M., et al. (2018) Colonisation with Multidrug-Resistant Organisms among Dialysis Patients at Universitas Academic Hospital. BMC Nephrology , 19, Article No. 363.
Scientific Review of Chad (2022) Bacteriological Profile of Germs Isolated in Urine (MDR and ESBL). RST Series B. 1-20.
Badran, A.A., Elgayar, F.A., Gouda, M.K. and Halfawy, N.M.E. (2025) Incidence of Extended Spectrum Β-Lactamase Genes (ESBLs) among Community and Health Care Infection in Mansoura University Hospital, Egypt. BMC Microbiology , 25, Article No. 316. https://doi.org/10.1186/s12866-025-04030-3
Ishani, A., Collins, A.J., Herzog, C.A. and Foley, R.N. (2005) Septicemia, Access and Cardiovascular Disease in Dialysis Patients: The USRDS Wave 2 Study. Kidney International , 68, 311-318. https://doi.org/10.1111/j.1523-1755.2005.00414.x
Asmare, Z., Erkihun, M., Abebe, W., Ashagre, A., Misganaw, T. and Feleke, S.F. (2024) Catheter-Associated Urinary Tract Infections in Africa: Systematic Review and Meta-Analysis. Infection , Disease & Health , 29, 172-179. https://doi.org/10.1016/j.idh.2024.02.005
European Centre for Disease Prevention and Control: An Agency of the European Union (2022) Surveillance Systems Overview for 2020. https://www.ecdc.europa.eu/en/publications-data/surveillance-systems-overview-2020
Weldetensae, M.K., Weledegebriel, M.G., Nigusse, A.T., Berhe, E. and Gebrearegay, H. (2023) Catheter-Related Blood Stream Infections and Associated Factors among Hemodialysis Patients in a Tertiary Care Hospital. Infection and Drug Resistance , 16, 3145-3156. https://doi.org/10.2147/idr.s409400
Opoku-Asare, B., Boima, V., Ganu, V.J., Aboagye, E., Asafu-Adjaye, O., Asare, A.A., et al. (2023) Catheter-Related Bloodstream Infections among Patients on Maintenance Haemodialysis: A Cross-Sectional Study at a Tertiary Hospital in Ghana. BMC Infectious Diseases , 23, Article No. 664. https://doi.org/10.1186/s12879-023-08581-6
Almenara-Tejederas, M., Rodríguez-Pérez, M.A., Moyano-Franco, M.J., de Cueto-López, M., Rodríguez-Baño, J. and Salgueira-Lazo, M. (2022) Tunneled Catheter-Related Bacteremia in Hemodialysis Patients: Incidence, Risk Factors and Outcomes. A 14-Year Observational Study. Journal of Nephrology , 36, 203-212. https://doi.org/10.1007/s40620-022-01408-8
Lewis, J.M., Feasey, N.A. and Rylance, J. (2019) Aetiology and Outcomes of Sepsis in Adults in Sub-Saharan Africa: A Systematic Review and Meta-Analysis. Critical Care , 23, Article No. 212. https://doi.org/10.1186/s13054-019-2501-y
Lewis, J.M., Abouyannis, M., Katha, G., Nyirenda, M., Chatsika, G., Feasey, N.A., et al. (2019) Population Incidence and Mortality of Sepsis in an Urban African Setting, 2013-2016. Clinical Infectious Diseases , 71, 2547-2552. https://doi.org/10.1093/cid/ciz1119