Xanthogranulomatous Pyelonephritis Associated with Crohn’s Disease and Primary Hyperparathyroidism
- 1 Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA
- 2 Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA
- 3 Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA
- 4 Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA
- 5 Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA
Abstract
We report on a case of unilateral and diffuse xanthogranulomatous pyelonephritis (XGP) associated with Crohn’s dis ease and primary hyperparathyroidism (HPT). The patient had undiagnosed primary HPT for at least a year prior to presentation. The co-existence of Crohn’s disease and primary HPT caused calcium oxalate stone likely by the known mechanism of hypercalcemia and hyperoxaluria respectively. The patient developed XGP, a rare disease, as a result of infected calcium oxalate stone which was treated with antibiotics and unilateral nephrectomy. To the best of our knowledge , this is the first case of XGP associated with Crohn’s disease and primary HPT.
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