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Post Hepatitis C Cirrhosis in Sub-Sahara Kidney Transplant, Treated with Sofosbuvir/Ledipasvir: Report of Case and Review of Literature
Nephrology and Dialysis Department of Teaching Hospital Sylvanus Olympio, University of Lomé, Lomé, Togo
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 1 Nephrology and Dialysis Department of Teaching Hospital Sylvanus Olympio, University of Lomé, Lomé, Togo
- 2 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 3 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 4 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 5 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 6 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
- 7 Néphrology, Hémodialysis and Organ Transplant Departement of Yopougon Teaching Hospital, University Felix Houphouet Boigny, Abidjan, Cote d’Ivoire
Open Journal of Nephrology·Volume 07 (2017)·Pages 95–100·Published 21 December 2017·DOI10.4236/ojneph.2017.74011
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Abstract
Background: Viral hepatitis C is a major public health problem in the world. The advent of direct-acting antivirals has revolutionized the taking in charge and prognosis of patients infected with the hepatitis C virus. The interest of this presentation is to draw attention to the problem of therapeutic care posed by viral hepatitis C in kidney transplant patients in C?te d’Ivoire, a country with limited resources where all direct-acting antivirals are not yet available. Patient observation: We report the case of a kidney transplant of 52 years old, chronic bearer of viral hepatitis C virus who after his kidney transplant presented, decompensated active cirrhosis. A treatment based on Sofosbuvir 400 mg/Ledipasvir 90 mg in this patient with genotype 2 for 12 weeks was initiated. A sustained virological response was observed 12 weeks after the end of treatment. Conclusion: Direct-acting antivirals offer the possibility of antiviral C treatment without interferon or ribavirin in cirrhotic renal transplant.
KeywordsCôte D’IvoireDirect-Acting AntiviralsKidney TransplantationViral Hepatitis C
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