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Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature
Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
General Surgery Service, Santa Casa de Ribeirão Preto, Ribeirão Preto, Brazil
São Paulo University (USP), Ribeirão Preto, Brazil
Faculty of Medicine, Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil
Pathology Department, Sírio-Libanes Hospital, São Paulo, Brazil
Faculty of Medicine, São Paulo University (USP), São Paulo, Brazil
Patholgy Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus, Amazonas, Brazil
Teaching and Research Department, Oncology Center Control Foundation (FCECON), Manaus, Amazonas, Brazil
Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
Urology Service, Hospital Pronto-Socorro 28 de Agosto, Manaus, Amazonas, Brazil
General Surgery Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
- 1 Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
- 2 Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
- 3 General Surgery Service, Santa Casa de Ribeirão Preto, Ribeirão Preto, Brazil
- 4 São Paulo University (USP), Ribeirão Preto, Brazil
- 5 Faculty of Medicine, Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil
- 6 Pathology Department, Sírio-Libanes Hospital, São Paulo, Brazil
- 7 Faculty of Medicine, São Paulo University (USP), São Paulo, Brazil
- 8 Patholgy Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
- 9 Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus, Amazonas, Brazil
- 10 Teaching and Research Department, Oncology Center Control Foundation (FCECON), Manaus, Amazonas, Brazil
- 11 Urology Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
- 12 Urology Service, Hospital Pronto-Socorro 28 de Agosto, Manaus, Amazonas, Brazil
- 13 General Surgery Service, Getúlio Vargas University Hospital (HUGV), Manaus, Amazonas, Brazil
Open Journal of Urology·Volume 12 (2022)·Pages 51–56·Published 10 January 2022·DOI10.4236/oju.2022.121005
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Abstract
Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. Case Presentation: We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. Conclusion: IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.
KeywordsOrchitisIgG4-Related DiseaseAutoimmuneTesticleInflammatory
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