Place of Open Radical Nephrectomy, in the Era of Laparoscopy in Subsaharian Africa
- 1 Departement of Urology, University of Lomé, Lomé, Togo
- 2 Departement of Urology, University of Lomé, Lomé, Togo
- 3 Department of Urology, University of Kara, Kara, Togo
- 4 Department of Urology, University of Kara, Kara, Togo
- 5 Departement of Urology, University of Lomé, Lomé, Togo
- 6 Department of Urology, University of Kara, Kara, Togo
Abstract
Introduction: Kidney cancer is discovered in Africa often at advanced or locally advanced stages. These patients could be treated by radical nephrectomy or cytoreductive nephrectomy. Open surgery still retains its place due to the technical difficulties which are linked to the stage of the tumors in this era where laparoscopy is becoming the gold standard. Through this study, we wanted to highlight the advanced stages of patients operated by open surgery in our institution rather than laparoscopy, however, with good results. Patients and Method: It was a retrospective study over a period of 5 years. Were included all patients in whom radical nephrectomy had been performed during this period. Results: Thirty-five (35) open radical nephrectomies for kidney cancer were performed. The average tumor size was 11.6 cm (±3.4 cm). The mean operating time was 169 min ± 63.4 min with extremes of 115 min (1 h 55 min) and 360 min (6 h). This duration was longer for large tumors (p = 0.002). Intraoperative incidents occurred in 4 patients (11.4%); it was a vena cava injury (02) and a spleen injury (02). Blood loss was estimated on average at 535 ml. The mean follow-up time was 19 ± 11 months. The overall survival rate was 90% at 3 months, 53% at 12 months and 35.4% at 24 months. Conclusion: The large size of kidney tumor found in Africa may constitute an obstacle to performing nephrectomies by laparoscopy. However, mastering the laparoscopic technique with appropriate equipment can help reduce operative morbidity.
- Sung, H., Ferlay, J., Siegel, R., Laversanne, M., et al. (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71, 209-249. https://doi.org/10.3322/caac.21660
- Bensalah, K., Albiges, L., Bernhard, J.C., et al. (2018) ccAFU Guidelines—Update 2018-2020: Management of Kidney Cancer. Progrès en Urologie, 28, 3-31. https://doi.org/10.1016/j.purol.2018.09.009
- Abu-Ghanem, Y., Fernández-Pello, S., Bex, A., et al. (2020) Limitations of Available Studies Prevent Reliable Comparison between Tumour Ablation and Partial Nephrectomy for Patients with Localised Renal Masses: A Systematic Review from the European Association of Urology Renal Cell Cancer Guideline Panel. European Urology Oncology, 3, 433-452. https://doi.org/10.1016/j.euo.2020.02.001
- Mikhail, D., Tabibzadeh, A., Rai, A. and Richstone, L. (2021) Laparoscopic Radical Nephrectomy. Journal of Endourology, 35, S83-S92. https://doi.org/10.1089/end.2021.0626
- Ndoye, M., Niang, L., Natchgande, M., Jalloh, M., Labou, I. and Gueye, S.M. (2014) Nephrectomy: Indications, Techniques and Results at the Department of Urology of hôpital general de Grand Yoff. Uro’Andro, 1, 120-128.
- Wang, D., Xiao, Z., Shou, J., Li, C. and Xing, N. (2019) Comparison of Laparoscopy and Open Radical Nephrectomy of Renal Cell Cancer. Open Medicine, 14, 392-397. https://doi.org/10.1515/med-2019-0040
- Badmust, A., Salakoa, A., Arogundadef, A., et al. (2008) Malignant Renal Tumors in Adults: A Ten-Year Review in a Nigerian Hospital. Saudi Journal of Kidney Diseases and Transplantation, 19, 120-126.
- Bellecl, L., Thoulouzan, M., Solera, P., Khedis, M., et al. (2012) Analysis of the Evolution of Surgical Practices for the Management of Primary Kidney Tumors in the Period 2006-2010: About a Series of 458 Consecutive Surgeries. Progrès en Urologie, 22, 520-528. https://doi.org/10.1016/j.purol.2012.04.004
- Cassell, A., Jalloh, M., Yunusa, B., et al. (2019) Management of Renal Cell Carcinoma-Current Practice in Sub-Saharan Africa. Journal of Kidney Cancer and VHL, 6, 1-9. https://doi.org/10.15586/jkcvhl.2019.122
- Avakoudjo, D.G.J., Hounnasso, P.P., Traore, M.T., et al. (2014) Experience with Managing Solid Kidney Tumours in Cotonou, Benin Republic. Journal of the West African College of Surgeons, 4, 100-111.
- James, F.B. (2008) Laparoscopic Radical Nephrectomy: Long-Term Outcomes. Current Opinion in Urology, 18, 139-144. https://doi.org/10.1097/MOU.0b013e3282f4a851