Therapeutic Aspects of Priapism at Soubré General Hospital: Six Clinical Cases
- 1 Urology-Andrology Department, Soubré General Hospital, Cheikh Anta Diop University of Dakar, Soubré, Côte d’Ivoire
- 2 Urology-Andrology Department, Idrissa Pouye General Hospital, Cheikh Anta Diop University of Dakar, Dakar, Sénégal
- 3 Surgery Department, Soubré General Hospital, Félix Houphouët Boigny University of Abidjan, Soubré, Côte d’Ivoire
- 4 Surgery Department, Soubré General Hospital, Félix Houphouët Boigny University of Abidjan, Soubré, Côte d’Ivoire
- 5 Surgery Department, Soubré General Hospital, Félix Houphouët Boigny University of Abidjan, Soubré, Côte d’Ivoire
- 6 Urology-Andrology Department, Aristide le Dantec University Hospital, Cheikh Anta Diop University of Dakar, Dakar, Sénégal
Abstract
Priapism is a common urological emergency in adults and rare in children in sub-Saharan Africa, where the main cause is sickle cell disease. We report six clinical cases, including two cases of low-flow, intermittent ischemic priapism in two children with sickle cell disease aged 10 and 12 years. Among the four other cases, a 46-year-old patient presented with a painful erection after taking herbal medicines to correct erectile dysfunction. Treatment was based on conservative methods, intracavernosal puncture and intracavernosal injection of sympathomimetic agents, and by pass surgery if necessary. The main lesson is that early conservative management can be valuable, as a complement to surgical options, in a context of limited resources.
- Qin, F., Qian, S.Q. and Yuan, J.H. (2013) Health Sciences. Journal of Pékin University , 45, 1001-1006.
- Tshipeta, L. (1980) Sickle Cell Priapism. Therapeutic Considerations in Light of 23 Cases. Journal of Urology ( Paris ), 86, 699-702.
- Falandry, L. (1999) Priapism: Treatment and Results. A Personal Series of 56 Cases. Progress in Urology , No. 9, 496-501.
- Fall, P.A., Diao, B., Ndoye, A.K., Ndiaye Diop, E., Sylla, C., Gueye, S.M., et al . (2005) Priapism: Clinical and Etiological Particularities. African Journal of Urology , 3, 186-190.
- Falandry, L., Berlizot, P., Fournier, R., Mechali, P., Thuret, R., Palascak, R., et al . (2000) Surgical Treatment of Priapism. Experience of 56 Cases in an African Setting. Tropical Medicine , 60, 70-74.
- Rudelle, E., Bitker, M.O., Saad, H. and Chatelain, C. (1993) Priapism. Urology , 10, 18-380.
- Farzampour, Z., Reimer, R.J. and Huguenard, J. (2015) Endozepines. In: Advances in Pharmacology , Elsevier, 147-164. https://doi.org/10.1016/bs.apha.2014.10.005
- Gravielle, M.C. (2016) Activation-Induced Regulation of GABAA Receptors: Is There a Link with the Molecular Basis of Benzodiazepine Tolerance? Pharmacological Research , 109, 92-100. https://doi.org/10.1016/j.phrs.2015.12.030
- Montague, D.K., Jarow, J., Broderick, G.A., Dmochowski, R.R., Heaton, J.P.W., Lue, T.F., et al . (2003) American Urological Association Guideline on the Management of Priapism. Journal of Urology , 170, 1318-1324. https://doi.org/10.1097/01.ju.0000087608.07371.ca
- Shrewsberry, A., Weiss, A. and Ritenour, C.W.M. (2010) Recent Advances in the Medical and Surgical Treatment of Priapism. Current Urology Reports , 11, 405-413. https://doi.org/10.1007/s11934-010-0142-4
- Capogrosso, P., Dimitropolous, K., Russo, G.I., Tharakan, T., Milenkovic, U., Cocci, A., et al . (2022) Conservative and Medical Treatments of Non-Sickle Cell Disease-Related Ischemic Priapism: A Systematic Review by the EAU Sexual and Reproductive Health Panel. International Journal of Impotence Research , 36, 6-19. https://doi.org/10.1038/s41443-022-00592-2
- Sidhu, A.S., Wayne, G.F., Kim, B.J., Anderson, A.G.S., Cordon, B.H., Caso, J.R., et al . (2018) The Hemodynamic Effects of Intracavernosal Phenylephrine for the Treatment of Ischemic Priapism. The Journal of Sexual Medicine , 15, 990-996. https://doi.org/10.1016/j.jsxm.2018.05.012