Clinical and Therapeutic Management of Male Infertility in Thies, Senegal
- 1 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 2 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 3 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 4 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 5 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 6 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 7 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 8 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 9 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 10 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 11 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
- 12 Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal
Abstract
Objective: To evaluate the clinical and therapeutic aspects of male subfertility in the Region of Thies. Patients and methods: This is a retrospective and analytical study involving patients followed for subfertility over a period of 4 years from January 2013 to November 2017 at the level of 3 health structures in the region of Thies. Results: During the period, we collected 201 patients. The average age was 38 ± 8.4 years with a greater distribution in the age group 30-39 years. Primary subfertility was predominant with 81.1% of cases. The average duration was 5 years. We found a history of urethritis (4%) and orchiepididymitis (2.5%). Thirty-three percent of patients presented a varicocele (67 cases). Cryptorchidism was recorded in 2% of cases, testicular hypotrophy in 18.4% and testicular atrophy in 1.5%. The spermogram identified oligospermia-like abnormalities in 40.8% of cases, azoospermia 22.4%, and hypospermia 4%. For the qualitative abnormalities, we recorded cases of asthenospermia in 60.2% of the cases or 121 patients, a necrospermia 58.2% and a teratospermia 20.4%. A combination of these abnormalities was also reported as astheno-necrospermia in 19.4% of cases, oligo-astheno-necrospermia 14.4%, oligo-asthenotera-necrospermia 10% and oligo astero-teratospermia in 2.5%. An assessment of FSH, LH and testosterone was performed in 5.9% of the cases, or 12 patients. Varicocelectomy was performed in 68.4% of cases 19 patients, and (medically) assisted procreation in 2 patients. We recorded 13 cases of pregnancy. Conclusion: Male hypofertility is a real problem of management, and requires a particular approach.
- Wagner, L., Tostain, J., et al. (2007) Varicocèle et infertilité masculine: Recommandation Comité Andrologie—AFU 2006. Progrès en Urologie, 17, 12-17. https://doi.org/10.1016/S1166-7087(07)92219-8
- Khallouk, A., Tazi, M.F., Fassi, M.J. and Farih, M.H. (2010) L’infertilité masculine: Physiopathologie, bilan et prise en charge. Espérance Médicale, 170, 421-429.
- Ndoye, M., Niang, L., Jalloh, M., Labou, I., Kane, R., Diaw, J., Ndiaye, A. and Guèye, S.M. (2008) Azoospermie au Sénégal: Quelle prise en charge à l’heure de l’ICSI? Andrologie, 18, 206-209. https://doi.org/10.1007/BF03040756
- Alsalkhan, B., Alrabeeah, K., Delouya, G. and Zini, A. (2016) Epidemiology of varicocèle. Asian Journal of Andrology, 18, 179-181. https://doi.org/10.4103/1008-682X.172640
- Inci, K. and Gunay, L.M. (2013) The Role of Varicocele Treatment in the Management of Non-Obstructive Azoospermia. Clinics, 68, 89-98. https://doi.org/10.6061/clinics/2013(Sup01)10
- Niang, L., Ndoye, M., Labou, I., Jalloh, M., Kane, R., Diaw, J.J., Ndiaye, A. and Guèye, S.M. (2009) Profil épidémiologique et clinique de l’infertilité masculine à l’hôpital général de Grand-Yoff, Sénégal: A propos de 492 cas. Basic and Clinical Andrology, 19, 103-107.
- Sakande, J., Kabre, E., Ekue, L.A., Ouedraogo, H.A. and Sawadogo, M. (2012) Relation entre les anomalies du spermogramme et les constituants biochimiques du liquide séminal de sujets consultant pour hypofertilité masculine à Ouagadougou. International Journal of Biological and Chemical Sciences, 6, 1167-1178.
- Wallerand, H., Bernardini, S., Charbannes, E. and Bittard, H. (2003) Infertilité masculine de cause génétique et biologie moléculaire. Progrès en Urologie, 13, 560-563.
- Diallo, M.S., Diallo, A.S., Fotso, P., Diallo, Y., Diao, B. and Faye, O. (2015) Semen Abnormality Patterns and Parameters in Male Partners of Infertile Couples in Dakar (Senegal). Open Journal of Urology, 5, 155-160. https://doi.org/10.4236/oju.2015.59024
- Eisenberg, M.L., Li, S., Behr, B., Cullen, M.R., Galusha, D., Lamb, D.J. and Lipshultz, L.I. (2014) Semen Quality, Infertility and Mortality in the USA. Human Reproduction, 29, 1567-1574. https://doi.org/10.1093/humrep/deu106
- Benazzouz, M.H., Essatara, Y., Sayegh, H., Iken, A., Benslimane, L. and Noulini, Y. (2014) Impact de la varicocèle sur le volume testiculaire et les paramètres spermatique. Pan African Medical Journal, 19, 334-337. https://doi.org/10.11604/pamj.2014.19.334.4693