Advanced Prostate Cancer: A Case Report

Abstract

There are few reported cases in the prostate adenocarcinoma literature with locoregional extension and normal prostate-specific antigen (PSA). We present the case of a patient with prostate adenocarcinoma and metastases with PSA values within the normal range, despite evidence of clinical and radiological progression of the disease. This is a 72-year-old patient presenting with a dysectatic syndrome in which there is a budding ulceration of the glans, an induration of the corpora cavernosa and whose rectal examination has objectified a malignant prostate. PSA was assayed at 3.47 ng/ml; prostatic biopsy and magnetic resonance imaging (MRI) revealed prostate cancer with extension to the urethral, cavernous and rectal areas. Hormone therapy was instituted and the course after two months was marked by the occurrence of several episodes of anemia treated by blood transfusion.