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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Yukari Ueda, Yasuhumi Shinmyouzu, Hikaru Nakayama, Tadatoshi Tanino, Eiko Sakurai, Eiichi Sakurai
We aimed to examine paracellular barrier function in cultured mouse lung microvascular endothelial cells (LMECs). The transcellular resistance of LMEC monolayers yielded an electrical resistance of approximately 19 Ω × cm 2 at days 6 - 7 in culture when the c…
Hiroshi Okada, Mitsuko Onda, Masaki Shoji, Kazuhiko Kotani, Takeo Nakayama, Yasushi Nakagawa, Naoki Sakane
Background: Community pharmacists should be involved in diabetes care, while there has been less evidence about whether a brief lifestyle intervention is effective for diabetes care in community pharmacies. Objectives: To examine the effects of brief lifestyl…
Seiichi Takeda, Takao Toda, Kazuki Nakamura
We conducted the novel synthesis of middle molecular weight heparinyl amino acid derivatives (MHADs) to reduce the adverse effect of heparin (HE) based on its anticoagulant activity. Subsequently, we investigated the radical scavenging effects of 12 kinds of…
Jacqueline Trivedi, Firuza Kharas, Sapna Parikh, Roda Dalal, Aurelio Lobo, Lyle Fonseca, Mahesh Jadhav, Shruta Dadarkar, Asha Almeida, Ankita Srivastava, Ashish Suthar
Tumor necrosis factor (TNF- α ) is a key regulator of the inflammatory and tissue destruc-tive pathways in rheumatoid arthritis (RA). The clinical success of anti-TNF- α and an-ti-IL-17 biologics has validated the concept that cytokine blockade is beneficial…
Takahiro Mizoguchi, Mitsue Ishisaka, Yui Kobatake, Hiroaki Kamishina, Yasuhiko Nishioka, Tsukasa Kirimoto, Masamitsu Shimazawa, Hideaki Hara
Dysphagia induces aspiration and causes aspiration pneumonia. There is no treatment for dysphagia fundamentally. Haloperidol reportedly induces dysphagia. In the present study, we established a haloperidol-induced dysphagia model in guinea pigs, and evaluated…
N. Tanna, T. Tatla, T. Winn, S. Chita, K. Ramdoo, C. Batten, J. Pitkin
Background: This paper reports findings from a literature review undertaken to assess the current evidence base for clinical medication review and falls in older people. This forms part of a larger, organisational supported project design work-stream, where t…
Nikoloz V. Gongadze, Tamara D. Kezeli, Galina V. Sukoyan, Zaza Chapichadze, Nino M. Dolidze, Makrine Mirziashvili, Mariam Chipashvili
Continuous treatment with organic nitrates causes nitrate tolerance and provides evidence for a relationship between mitochondrial complex 1 activity and mitochondrial aldehyde dehydrogenase-2 (ALDH-2) with disturbances of the hemodynamics reaction during nit…
Jane J. Xu, Ilene Burton, Wayne J. Tymchak, Glen J. Pearson
Background: Allograft coronary artery disease (ACAD) is a common cause of morbidity and mortality post-orthotopic heart transplantation (OHT). ACAD progression may be reduced by modifying cardiovascular risk factors, such as hyperlipidemia and hypertension. W…
Xiaoyan Chen, Roy A. Lysaa, Ragnhild Jaeger, Emanuel Boadu, Georg Sager
Background: Previous studies of patients with acute leukemia showed that plasma cGMP levels were markedly elevated before treatment, fell after successful therapy but increased after relapse. In many cells high concentrations of GMP have an antiproliferative…
Rafeeq Alam Khan, Maryam Aslam, Shadab Ahmed
In current study toxicological profile of a commonly used herbal formulation was evaluated that is used extensively for gynecological disorders like menorrhagia, metrorrhagia, leucorrhea, irregular menstrual cycle, pre-menstrual syndrome and post-menopausal b…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).