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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Tianxiu Qian, 1 1, Pou Kuan Leong, Kam Ming Ko, Wan Chan
Schisandrin B (Sch B) is one of the active dibenzocyclooctadiene lignans found in the Schisandrae Fructus. Experimental studies have shown that Sch B possesses various pharmacological properties, including anti-cancer, neuroprotective and nephroprotective act…
Raúl Loera-Valencia, Josué Obed Jaramillo-Polanco, Andrómeda Linan-Rico, María Guadalupe Nieto Pescador, Juan Francisco Jiménez Bremont, Carlos Barajas-López
Purinergic P2X receptors are a family of ligand-gated cationic channels activated by extracellular ATP. P2X subunit protein sequences are highly conserved between vertebrate species. However, they can generate a great diversity of coding splicing variants to…
Tomoya Sasahara, Natsumi Ohkura, Mariko Shin, Akira Onodera, Katsutoshi Yayama
Inhibition of protein tyrosine phosphatase by orthovanadate induces vasoconstriction, which is mediated by the Rho kinase-dependent inactivation of myosin light chain phosphatase (MLCP) via signaling downstream of Src-induced activation of the epidermal growt…
Melappa Govindappa, Kavya C. Hemmanur, S. Nithin, Chandrappa Chinna Poojari, Gopalakrishna Bhat, K. Channabasava
5 totally different endophytic fungal species were isolated from bark and leaf parts of Calophyllum inophyllum . Leaf part yielded Trichoderma harzianum and Alternaria species, whereas bark showed the presence of Fusarium species, Aspergillus species and unid…
Umamahesh Balekari, Ciddi Veeresham
Since ancient times, traditional medicines have been in the usage for the treatment of Diabetes mellitus. An edible fruit from traditional medicinal plant Capparis zeylanica (CZ) was studied for its anti diabetic, insulin secretagogue activities and mechanism…
Yoshiyuki Hattori, Shohei Arai, Takuto Kikuchi, Megumi Hamada, Ryou Okamoto, Yoko Machida, Kumi Kawano
Previously, we developed a novel siRNA transfer method to the liver by sequential intravenous injection of poly-L-glutamic acid (PGA) and cationic liposome/siRNA complex (cationic lipoplex). In this study, we examined the effects of the charge ratio (+/-) of…
Christopher Oswald Migoha, Eliangiringa Kaale, Godliver Kagashe
Omeprazole is a potent proton pump inhibitor with powerful inhibition of secretion of gastric juice. Oral site-specific drug delivery systems have recently attracted a great interest for the local treatment of bowel disease and for improving systemic absorpti…
Xiaohui Yin, Xiuxia Gu, Yun He, Di Zhu, Jie Chen, Jue Wu, Xueqin Feng, Jinhao Li, Caiping Mao, Zhice Xu
Objective—The umbilical cord is a critical pathway between mothers and fetuses, and regulations of umbilical vessel tension are important for fetal growth. Shengmai is an herbal medicine being used in treatments of cardiovascular diseases. However, effects of…
Patrick Rutendo Matowa
Background: Cardiac failure treatment largely focused on symptomatic relief at the expense of the address of the underlying disease process of cardiac remodelling. This old wisdom of practice has been turned around by clinical research findings that have show…
Prosper Obunikem Uchechukwu Adogu, Ifeoma A. Njelita, Nonye Bibiana Egenti, Chika Florence Ubajaka, Ifeoma A. Modebe
Background: Abuse of medicines is becoming a serious problem in many parts of the world, with negative consequences ranging from addiction, psychosis, cardiovascular complications, and premature deaths from unintentional overdose. Objectives: The objective of…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
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Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
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