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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Byung-Yoon Cha, Wen Lei Shi, Kotaro Watanabe, Takayuki Yonezawa, Toshiaki Teruya, Kiyotake Kiyotake, Yuichi Ishikawa, Shigeru Nishiyama, Kazuo Nagai, Je-Tae Woo
Platelet-derived growth factor (PDGF)-BB is one of the most potent factors in the development and progression of various vascular disorders, such as atherosclerosis and restenosis. PDGF is a major stimulant for vascular smooth muscle cells (VSMCs) proliferati…
Leila Adibi, Maryam Khosravi, Shahrzad Khakpour, Hedayat Sahraei, Mahsa Hadipour Jahromy
Due to our previous findings about the role of GABAegic neurotransmission in anxiolytic effects of Citrus aurantium L. essential oil, we are now presenting flomazenil interaction with this herb, as an antagonist of benzodiazepines at GABA receptor. The study…
Froylán Ibarra-Velarde, Yazmin Alcala-Canto, Yolanda Vera-Montenegro
Acaricide resistance is a major problem that hinders the control of the cattle tick Rhipicephalu s (Boophilus) microplus in Mexico. Permethrin (P), cypermethrin (C) and zeta-cypermethrin (Z) have been used to control R. (B.) microplus , and tick populations h…
Silvia Reina, Cecilia Pisoni, Alicia Eimon, Carolina Carrizo, Roberto Arana, Enri Borda
Background : Evidences have shown that anti-M 3 muscarinic acetylcholine receptor IgG (anti-M 3 mAChR IgG) are clinically useful autoantibody that exert a cholinergic pharmacologic effect binding and interacting with M 3 mAChR at the level of exocrine gland (…
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri, Obianime Atuboyedia Wolfe
The chronic toxicological profile of disulfiram/copper gluconate (DSF/CG) combination was investigated in a 90 day time and dose dependent study. A total of 148 rats weighing 260 - 300 g were used for this study; 60 for the pilot study and 88 for the chronic…
Ahmed M. Soliman, Mohamed Aboubakr, Mohamed El-Hewaity
Aims: The present study was designed to assess the comparative bio-equivalence of Doxysol ® and Doxymed ® in healthy broiler chickens after oral administration of both products in a dose of 20 mg doxycycline/kg.b.wt. Materials and Methods: Twenty broile…
Patience O. Obih, Barry J. Potter
To examine the pro- and anti-oxidant properties of nitric oxide (NO) production in alcoholic liver disease, we compared the effects of ethanol pretreatment (24 hrs, 100 mM concentration in a dedicated CO 2 incubator) on the induction of inducible NO synthase…
Rosivaldo S. Borges, Tainá G. Barros, Glaécia A. N. Pereira, João Batista Jr., Raimundo F. G. P. Beleza Filho, Andrex A. S. Veiga, Moisés Hamoy, Vanessa J. Mello, Albérico B. F. da Silva, Carlos A. L. Barros
The paracetamol has more antioxidant properties than the salicylic acid on the several oxidative stress-forced models and one possible mechanism is due to electron or hydrogen transfer by the evaluated hydroxyl radicals. The antioxidant mechanism for the comp…
Ian Humphery-Smith
Bacteriophages have a potentially important role to play in reducing the global incidence of Hospital Acquired Infection (HAI). Their use should be focused on reducing the use and over-use of antibiotics as part of integrated control measures in conjunction w…
Tuukka A. Helin, Niko Wickholm, Hannu Kautiainen, Heikki Vapaatalo
Experimental and clinical studies have shown that long term anticoagulation therapy with warfarin can induce vascular calcification which is preventable by vitamin K. Osteoporosis has been shown to be associated with vascular calcification. In the present stu…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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