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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Steven Lai Hing, Akshaya Ravichandran, Jerome Escano, Jim Cooley, Frank Austin, Shi-En Lu, Stephen Pruett, Leif Smith
Occidiofungin, a glyco-lipopeptide obtained from the liquid culture of Burkholderia contaminans MS14, has been identified as a novel fungicide. The natural product was shown to have a minimal amount of toxicity in a previous mouse toxicity study following int…
Valentina Bashkatova, Sergey Sudakov, Galina Nazarova, Elena Alexeeva
The objective of these experiments was to study the effects of ethanol on the anxiety level, activity, metabolic rate, and feeding and drinking behaviors of rats that were chronically treated with nicotine. The chronic intake of nicotine changed the effects o…
Rupal Patel Mansukhani, Lucio R. Volino, 1 1
Objective: To review the literature for the emerging oral anticoagulants, dabigatran, rivaroxaban, and apixaban currently available in the United States. Data Source: A literature review was performed in MEDLINE (1947–July 2014) using the keywords atrial fibr…
Mst. Marium Begum, A. F. M. Towheedur Rahman, Saiful Islam, Md. Asaduzzaman, Hazrat Ali, Yusuf Ali, Shaheda Zannah, A. H. M. Khurshid Alam, Aziz Abdur Rahman, Mamunur Rashid
The aim of the current study is to investigate the effect of combination of glibenclamide; an antidiabetic drug and simvastatin; a HMG-CoA reductase inhibitor on long-term (four weeks) alloxan-induced diabetes rats (ADRs). Methods: Alloxan (120 mg/kg body wei…
Lucio R. Volino, Eva Y. Pan, Rupal Patel Mansukhani
Diabetes mellitus continues to be a major health issue worldwide. Despite all of the treatment options available on the market, many patients with diabetes fail to reach their treatment goals. Novel agents such as the Sodium-Glucose Cotransporter 2 (SGLT2) in…
Addai-Mensah Donkor, Micheal Spelios, Michalakis Savva
In this paper, a novel series of bis [(aminoethyl)]-amine cationic lipid derivatives have been synthesized and identified to purity by NMR and Elemental analysis. B16-F0 cells were transfected with cationic lipid/pEGFP-N1 and cationic lipid/ ß -gal lipopl…
Maria Trigub, Vladinir Kudrin, Valentina Bashkatova, Petr Klodt, Sergey Sudakov
Individual differences in behavioral characteristics or initial responses to abused drugs had been recently demonstrated to have predictive value in the propensity of later abuse. The research described here was initiated to determine the initial response of…
Patience O. Obih, Adebayo Oyekan
PPARs are ligand-activated nuclear transcription factors that regulate β -oxidation of fatty acids in the cardiovascular system and PPAR α isoform is a putative target for regulation of cardiovascular function. High salt diet is an injurious stimulus to cardi…
Iandra Holzmann, Daiane Cattani, Micheli Corso, Daiane Perondi, Sabrina Zanella, Cristiani Burger, Luiz Carlos Klein Júnior, Valdir Cechinel Filho, Sully M. Cruz, Miguel F. Torres, Armando Cáceres, Márcia Maria de Souza
Bourreria huanita (Lex.) Hemsl. (Boraginaceae) is a very rare and highly appreciated tree in Mesoamerica for its medicinal properties and beauty. It grows in a region extending from central Mexico to Costa Rica. Ethnobotanical surveys have shown that the infu…
Caitlin E. McCarthy, Danielle M. Candelario, Mei T. Liu
Anxiety disorders comprise the most common group of mental disorders to affect the general population in the United States. These disorders are heterogeneous in nature, highly comorbid with one another, and pose a degree of difficulty regarding diagnosis and…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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