A Traumatic Brain Injury (TBI) is an injury to the brain caused by an external force (vehicle, accidents, violence, sports injuries, industrial accidents, falls). Brain trauma can occur either from an object penetrating the skull or from rapid acceleration (speeding up), or deceleration (slowing down or stopping suddenly) of the brain. Traumatic Brain Injury (TBI) is a major cause of mortality and disability, especially in children and young adults. Based on the Glasgow Coma Scale (GCS), the neurological scale used to measure a person’s level of consciousness after a brain injury, traumatic brain injury is classified as: mild (GCS 13 - 15), moderate (GCS 9 - 12), severe (GCS 8 or less), and evaluates the following functions: Eye Opening (E), Motor Response (M), and Verbal Response (V), to determine a patient’s overall GCS, add together the scores from eye opening, motor response and verbal response. Scores range from 3 to 15. A score of 8 or less signifies coma. Symptoms can vary depending on the severity of the head injury. An individual with a mild traumatic brain injury can remain conscious, or may experience a loss of consciousness for a few seconds or minutes. Other symptoms may include headache, confusion, dizziness, vision changes, ringing in the ears or changes in hearing, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and cognitive and/or executive functioning problems. People with a moderate or severe traumatic brain injury may show the same symptoms, but may also have a headache that gets worse, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation. Attention-Deficit/Hyperactivity Disorder secondary to Traumatic Brain Injury (TBI) is one of the most common neurobehavioral consequences of Traumatic Brain Injury (TBI), occurring in 20% to 50% of individual’s post-injury ( Irastorza, 2011 ). Some of the most persistent problems include impairment in memory, attention and concentration, language, executive skills, social judgment, social behavior, and impulsiveness. Previous studies have shown that Traumatic Brain Injury (TBI) is a major cause of mental health problems and increases the risk of Attention-Deficit/Hyperactivity Disorder ( Schachar et al., 2015 ). According to studies ( Ilie et al., 2015 ), physical brain injury contributes to the development of Attention-Deficit/Hyperactivity Disorder. Because the risk of Attention-Deficit/Hyperactivity Disorder development after Traumatic Brain Injury (TBI) remains high over an extended period, and some of the most persistent problems include impairment in memory, attention and concentration, language, executive skills, social judgment, social behavior, and impulsiveness; this master thesis shows the importance of an early prompt intervention after brain injury, and the need to establish a therapeutic plan in order to treat the Attention-Deficit/Hyperactivity Disorder development and evolution. The purpose of the present study is to investigate the association between Traumatic Brain Injury (TBI) and Attention-Deficit/Hyperactivity Disorder, and also to show the importance of prompt intervention and preventive therapy in order to stop the Attention-Deficit/Hyperactivity Disorder development and evolution.
Amen, D. G. (2013). Healing ADD. Penguin Random House LLC.
American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596
Auclair, V., Harvey, P. O., & Lepage, M. (2016). La thérapie cognitive-comportementale dans le traitement du TDAH chez l’adulte [Cognitive Behavioral Therapy and the Treatment of ADHD in Adults]. Sante Mentale au Quebec, 41, 291-311. https://pubmed.ncbi.nlm.nih.gov/27570962 https://doi.org/10.7202/1036976ar
Backeljauw, B., & Kurowski, B. G. (2014). Interventions for Attention Problems after Pediatric Traumatic Brain Injury: What Is the Evidence? PM & R: The Journal of Injury, Function, and Rehabilitation, 6, 814-824. https://doi.org/10.1016/j.pmrj.2014.04.004
Barman, A., Chatterjee, A., & Bhide, R. (2016). Cognitive Impairment and Rehabilitation Strategies after Traumatic Brain Injury. Indian Journal of Psychological Medicine, 38, 172-181. https://doi.org/10.4103/0253-7176.183086
Bos, D. J., Oranje, B., Veerhoek, E. S., Van Diepen, R. M., Weusten, J. M., Demmelmair, H., Koletzko, B., de Sain-van der Velden, M. G., Eilander, A., Hoeksma, M., & Durston, S. (2015). Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder. Neuropsychopharmacology, 40, 2298-306. https://doi.org/10.1038/npp.2015.73
Centers for Disease Control and Prevention (2020). Attention-Deficit/Hyperactivity Disorder (ADHD). https://www.cdc.gov
Center-TBI (2020). 10 Facts about TBI. https://www.center-tbi.eu
Cherkasova, M., Sulla, E. M., Dalena, K. L., Pondé, M. P., & Hechtman, L. (2013). Developmental Course of Attention Deficit Hyperactivity Disorder and Its Predictors. Journal of Canadian Academy of Child and Adolescent Psychiatry, 22, 47-54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565715/#b20-ccap22_1p0047
Cueli, M., Rodríguez, C., Cabaleiro, P., García, T., & González-Castro, P. (2019). Differential Efficacy of Neurofeedback in Children with ADHD Presentations. Journal of Clinical Medicine, 8, 204. https://doi.org/10.3390/jcm8020204
Doidge, N. (2010). The Brain That Changes Itself. Stories of Personal Triumph from the Frontiers of Brain Science. Penguin Books.
Enriquez-Geppert, S., Smit, D., Pimenta, M. G., & Arns, M. (2019). Neurofeedback as a Treatment Intervention in ADHD: Current Evidence and Practice. Current Psychiatry Reports, 21, 46. https://doi.org/10.1007/s11920-019-1021-4
Gawrilow, C., Stadler, G., Langguth, N., Naumann, A., & Boeck, A. (2016). Physical Activity, Affect, and Cognition in Children with Symptoms of ADHD. Journal of Attention Disorder, 20, 51-62. https://doi.org/10.1177/1087054713493318
Halperin, J. M., Bédard, A. C., & Curchack-Lichtin, J. T. (2012). Preventive Interventions for ADHD: A Neurodevelopmental Perspective. Neurotherapeutics, 9, 531-541. https://doi.org/10.1007/s13311-012-0123-z
Hiploylee, C., Dufort, P. A., Davis, H. S., Wennberg, R. A., Tartaglia, M. C., Mikulis, D., Hazrati, L. N., & Tator, C. H. (2017). Longitudinal Study of Postconcussion Syndrome: Not Everyone Recovers. Journal of Neurotrauma, 34, 1511-1523. https://doi.org/10.1089/neu.2016.4677
Ilie, G., Vingilis, E. R., Mann, R. E., Hamilton, H., Toplak, M., Adlaf, E. M., Kolla, N., Ialomiteanu, A., van der Mass, M., Asbridge, M., Vingilis-Jaremko, L., Rehm, J., & Cusimano, M. D. (2015). The Association between Traumatic Brain Injury and ADHD in a Canadian Adult Sample. Journal of Psychiatric Research, 69, 174-179. https://doi.org/10.1016/j.jpsychires.2015.08.004
Irastorza, L. (2011). Treatment of ADHD Secondary to Traumatic Brain Injury. European Psychiatry, 26, 1246-1246. https://doi.org/10.1016/S0924-9338(11)72951-0
Kurowski, B. G., Taylor, H. G., Yeates, K. O., Walz, N. C., Stancin, T., & Wade, S. L. (2011). Caregiver Ratings of Long-Term Executive Dysfunction and Attention Problems after Early Childhood Traumatic Brain Injury: Family Functioning Is Important. PM & R: The Journal of Injury, Function and Rehabilitation, 3, 836-845. https://doi.org/10.1016/j.pmrj.2011.05.016
Li, L., Li, Y., McDonald, C., & Liu, J. (2018). Parent-Reported Mild Head Injury History in Children: Long-Term Effects on Attention-Deficit Hyperactivity Disorder. Global Pediatric Health, 5, 2333794X18756465. https://doi.org/10.1177/2333794X18756465
Little, A., Byrne, C., & Coetzer, R. (2021). The Effectiveness of Cognitive Behaviour Therapy for Reducing Anxiety Symptoms Following Traumatic Brain Injury: A Meta-Analysis and Systematic Review. NeuroRehabilitation, 48, 67-82. https://doi.org/10.3233/NRE-201544
Lutz, A., Jha, A. P., Dunne, J. D., & Saron, C. D. (2015). Investigating the Phenomenological Matrix of Mindfulness-Related Practices from a Neurocognitive Perspective. The American Psychologist, 70, 632-658. https://doi.org/10.1037/a0039585
Mahone, E. M., & Denckla, M. B. (2017). Attention-Deficit/Hyperactivity Disorder: A Historical Neuropsychological Perspective. Journal of the International Neuropsychological Society, 23, 916-929. https://doi.org/10.1017/S1355617717000807
Max, J. E., Schachar, R. J., Levin, H. S., Ewing-Cobbs, L., Chapman, S. B., Dennis, M., Saunders, A., & Landis, J. (2005). Predictors of Attention-Deficit/Hyperactivity Disorder within 6 Months after Pediatric Traumatic Brain Injury. Journal of the American Academy Child and Adolescent, 44, 1032-1040. https://doi.org/10.1097/01.chi.0000173293.05817.b1
Mitchell, J. T., Zylowska, L., & Kollins, S. H. (2015). Mindfulness Meditation Training for Attention-Deficit/Hyperactivity Disorder in Adulthood: Current Empirical Support, Treatment Overview, and Future Directions. Cognitive and Behavioral Practice, 22, 172-191. https://doi.org/10.1016/j.cbpra.2014.10.002
Morse, A. M., & Garner, D. R. (2018). Traumatic Brain Injury, Sleep Disorders, and Psychiatric Disorders: An Underrecognized Relationship. Medical Sciences, 6, 15. https://doi.org/10.3390/medsci6010015
Narad, M. E., Kennelly, M., Zhang, N., Wade, S. L., Yeates, K. O., Taylor, H. G., Epstein, J. N., & Kurowski, B. G. (2018). Secondary Attention-Deficit/Hyperactivity Disorder in Children and Adolescents 5 to 10 Years after Traumatic Brain Injury. JAMA Pediatrics, 172, 437-443. https://doi.org/10.1001/jamapediatrics.2017.5746
Pakdaman, F., Irani, F., Tajikzadeh, F., & Jabalkandi, S. A. (2018). The Efficacy of Ritalin in ADHD Children under Neurofeedback Training. Neurological Sciences, 39, 2071-2078. https://doi.org/10.1007/s10072-018-3539-3
Pires, T. de O., da Silva, C. M., & de Assis, S. G. (2013). Association between Family Environment and Attention Deficit Hyperactivity Disorder in Children-Mothers’ and Teachers’ Views. BMC Psychiatry, 13, 215. https://doi.org/10.1186/1471-244X-13-215
Russell, A. E., Ford, T., & Russell, G. (2015). Socioeconomic Associations with ADHD: Findings from a Mediation Analysis. PLoS ONE, 10, e0128248. https://doi.org/10.1371/journal.pone.0128248
Safren, S. A., Sprich, S., Mimiaga, M. J., Surman, C., Knouse, L., Groves, M., & Otto, M. W. (2010). Cognitive Behavioral Therapy vs Relaxation with Educational Support for Medication-Treated Adults with ADHD and Persistent Symptoms: A Randomized Controlled Trial. JAMA, 304, 875-880. https://doi.org/10.1001/jama.2010.1192
Sasmita, A. O., Kuruvilla, J., & Ling, A. P. K. (2018). Harnessing Neuroplasticity: Modern Approaches and Clinical Future. International Journal of Neuroscience, 128, 1061-1077. https://doi.org/10.1080/00207454.2018.1466781
Schachar, R. J., Park, L. S., & Dennis, M. (2015). Mental Health Implications of Traumatic Brain Injury (TBI) in Children and Youth. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 24, 100-108. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558980
Schönenberg, M., Wiedemann, E., Schneidt, A., Scheeff, J., Logemann, A., Keune, P. M., & Hautzinger, M. (2017). Neurofeedback, Sham Neurofeedback, and Cognitive-Behavioural Group Therapy in Adults with Attention-Deficit Hyperactivity Disorder: A Triple-Blind, Randomised, Controlled Trial. The Lancet Psychiatry, 4, 673-684. https://doi.org/10.1016/S2215-0366(17)30291-2
Seyedi, M., Gholami, F., Samadi, M., Djalali, M., Effatpanah, M., Yekaninejad, M. S., Hashemi, R., Abdolahi, M., Chamari, M., & Honarvar, N. M. (2019). The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder. CNS & Neurological Disorders Drug Targets, 18, 496-501. https://doi.org/10.2174/1871527318666190703103709
Stojanovski, S., Felsky, D., Viviano, J. D., Shahab, S., Bangali, R., Burton, C. L. et al. (2019). Polygenic Risk and Neural Substrates of Attention-Deficit/Hyperactivity Disorder Symptoms in Youths with a History of Mild Traumatic Brain Injury. Biological Psychiatry, 85, 408-416. https://doi.org/10.1016/j.biopsych.2018.06.024
Thapar, A., & Stergiakouli, E. (2010). An Overview on the Genetics of ADHD. Acta Psychologica Sinica, 40, 1088-1098. https://doi.org/10.3724/SP.J.1041.2008.01088
Yang, L. Y., Huang, C. C., Chiu, W. T. et al. (2016). Association of Traumatic Brain Injury in Childhood and Attention-Deficit/Hyperactivity Disorder: A Population-Based Study. Pediatric Research, 80, 356-362. https://doi.org/10.1038/pr.2016.85
Zang, Y. (2019). Impact of Physical Exercise on Children with Attention Deficit Hyperactivity Disorders. Medicine, 98, e17980. https://doi.org/10.1097/MD.0000000000017980
Zillmer, E., Spiers, M., & Culbertsone, W. (2008). Principles of Neuropsychology (2nd ed.). Thomson Wadsworth.