Lesions resulting from duodenal involvement are rare. Their diagnosis and management remain difficult because of the topographic location of most of th e duodenum in the retroperitoneum. We report a case of isolated duoden al rupture. At the time of the first operation, the duodenal lesion had gon e unnoticed. During our management, we discovered a rupture of the lower knee of the second duodenum and we performed a triple anastomosis after the closure of the ends (proximal and distal). The immediate postoperative course was complicated by the death of the patient on the second day of surgery. Duodenal lesions have much mortality which is increased by the delay in diagnosis and management.
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