Comprehensive Surgical Management of Grade III and IV Gynecomastia: Our Approach and Experience
- 1 First Faculty of Medicine, Charles University, Prague, Czech Republic
- 2 School of anesthesiology, Iran University of Medical Sciences, Tehran, Iran
- 3 Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
- 4 First Faculty of Medicine, Charles University, Prague, Czech Republic
Abstract
Background: Gynecomastia, the benign proliferation of male breast glandular tissue, is often associated with adiposity and skin redundancy. Surgical intervention for advanced grades (III and IV) remains challenging due to significant skin excess, glandular ptosis, and descent of the nipple-areolar complex (NAC). Objective: To present our experience and novel techniques in the management of Grade III and IV gynecomastia over a one-year period. Methods: Seventy-three patients with gynecomastia, treated between February 2024 and 15 May 2025, were prospectively evaluated. Patients were categorized using Simon’s classification. Data collected included demographic information, comorbidities, and surgical outcomes. Surgical techniques varied by grade, with a unique approach employed for Grades III and IV involving quilting sutures and bipedicle NAC flaps. Postoperative outcomes and satisfaction levels were assessed over a follow-up period of 3 - 12 months. Results: Of the 73 patients, the mean age was 27.5 years (range: 18 - 51) and BMI ranged from 21 to 35. High satisfaction rates were reported by patients (95%) and surgeons (91%). Complications were minimal, and scars were generally well-tolerated and faded away after few weeks, particularly in patients with chest hair. Conclusion: To our best knowledge, this is the first paper that reports one-stage surgery for grade 4 Gynecomastia. Our one-stage surgical technique offers a reliable, aesthetically pleasing solution for advanced gynecomastia. The use of quilting sutures (has been reported few in other surgeries and not in Gynecomastia) and bipedicle flaps for NAC repositioning effectively addresses drooping excess skin and glandular ptosis while minimizing visible scarring.
- Nuzzi, L.C. and Firriolo, J.M. (2018) The Psychological Burden of Gynecomastia: A Systematic Review. Plastic and Reconstructive Surgery , 141, 1141-1150.
- Petty, P.M., Solomon, M., Buchel, E.W. and Tran, N.V. (2010) Gynecomastia: Evolving Paradigm of Management and Comparison of Techniques. Plastic and Reconstructive Surgery , 125, 1301-1308. https://doi.org/10.1097/prs.0b013e3181d62962
- Narula, H.S. and Carlson, H.E. (2014) Gynaecomastia—Pathophysiology, Diagnosis and Treatment. Nature Reviews Endocrinology , 10, 684-698. https://doi.org/10.1038/nrendo.2014.139
- Zocchi, M.L. and Zuliani, F. (2018) Body Contouring after Massive Weight Loss: The Gynecomastia Challenge. Clinics in Plastic Surgery , 45, 89-99.
- Dickson, G., Rowe, M. and Lee, M. (2021) Modern Gynecomastia: Incidence and Pathophysiology. British Journal of Surgery , 108, 1055-1061.
- Rohrich, R.J., Ha, R.Y., Kenkel, J.M. and Adams, W.P. (2003) Classification and Management of Gynecomastia: Defining the Role of Ultrasound-Assisted Liposuction. Plastic and Reconstructive Surgery , 111, 909-923. https://doi.org/10.1097/01.prs.0000042146.40379.25
- Lista, F., Ahmad, J. and Tarshis, J. (2006) Redefining Gynecomastia Treatment: A Safe and Effective Technique for Liposuction and Excision of Breast Tissue. Plastic and Reconstructive Surgery , 117, 722-730.
- Teimourian, B. and Perlman, R. (1983) Surgical Correction of Gynecomastia through A Periareolar Incision. Aesthetic Plastic Surgery , 7, 39-42.
- Al-Attar, A., Mess, S.A. and Rohrich, R.J. (2017) Classification and Management of Gynecomastia: A Literature Review. Aesthetic Surgery Journal , 37, 743-757.
- Spear, S.L., et al . (2009) A Retrospective Analysis of Gynecomastia Surgical Techniques. Annals of Plastic Surgery , 62, 360-363.
- Pollock, H. and Pollock, T. (2000) Progressive Tension Sutures in Abdominoplasty: A Review of 597 Consecutive Cases. Aesthetic Surgery Journal , 20, 122-133.
- Cagli, B., et al . (2016) Efficacy of Progressive Tension Sutures in Reducing Seroma Formation after Body Contouring Surgery. Aesthetic Plastic Surgery , 40, 20-26.
- Del Vecchio, D.A. (2003) Inframammary Skin Resection with Free Nipple Grafting for Correction of Severe Gynecomastia. Plastic and Reconstructive Surgery , 112, 2044-2049.
- Oranges, C.M., et al . (2017) Surgical Management of Gynecomastia in Postbariatric Patients. Obesity Surgery , 27, 2469-2475.