Endovascular Repair of Abdominal Aortic Aneurysm May Not Provide Long-Term Survival Benefit
- 1 Department of Vascular Surgery, St George Private Hospital, Kogarah, Australia
- 2 Department of Vascular Surgery, St George Private Hospital, Kogarah, Australia
Abstract
Purpose: To investigate the long term survival benefit for the treatment of abdominal aortic aneurysmal (AAA) disease with Endovascular Aneurysm Repair (EVAR). Our hypothesis is that patients undergoing EVAR have an equivalent survival to an age matched population. Methods: Between 1997 and 2014 all patients treated for an AAA with EVAR by a single surgeon were prospectively followed and at 12 monthly intervals ultrasonography was utilised to assess the size of the aorta after treatment. Data from the Births, Deaths and Marriages was also collected regarding the survival of these patients. As of 2003 all patients with AAA were treated electively with EVAR. Results: There were a total of 145 patients treated with EVAR for AAA during the study period, 143 who survived the 30-day post-operative period. The long-term survival following EVAR at one year was 95% (95% C.I.: 88% to 97%), at 5 years 56% (95% C.I.: 42% to 64%), and at 10 years 28% (95% C.I.: 17% to 42%). Compared to an age-matched population the EVAR group had a lower than expected long term survival (P < 0.0001). Discussion: EVAR for the treatment of abdominal aortic aneurysms can be achieved with acceptable 30 day survival and freedom from aneurysm related death. However selection of patients for EVAR may significantly effect long-term survival if patients are fit for EVAR but not open operation. The question arises as to whether EVAR should be performed in patients with questionable long-term survival, even if they are fit for this procedure.
- Norman, P.E. and Powell, J.T. (2007) Contemporary Reviews in Cardiovascular Medicine, Abdominal Aortic Aneurysm, The Prognosis in Women Is Worse Than In Men. Circulation, 115, 2865-2869. http://dx.doi.org/10.1161/CIRCULATIONAHA.106.671859
- Greenhalgh, R.M. (2004) Comparison of Endovascular Aneurysm Repair with Open Repair in Patients with Abdominal Aortic Aneurysm (EVAR Trial 1), 30-Day Operative Mortality Results: Randomised Controlled Trial. The Lancet, 364, 843-848. http://dx.doi.org/10.1016/S0140-6736(04)16979-1
- Prinssen, M., et al. (2004) A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms. New England Journal of Medicine, 351, 1607-1618. http://dx.doi.org/10.1056/NEJMoa042002
- De Bruin, J.L., Baas, A.F. and Buth, J. (2010) Long-Term Outcome of Open or Endovascular Repair of Abdominal Aortic Aneurysm. Journal of Vascular Surgery, 52, 518.
- EVAR Trial Participants (2005) Endovascular Aneurysm Repair and Outcome in Patients Unfit for Open Repair of Abdominal Aortic Aneurysm (EVAR Trial 2): Randomized Controlled Trial. The Lancet, 365, 2187-2192. http://dx.doi.org/10.1016/S0140-6736(05)66628-7
- Peppelenbosch, N., et al. (2004) Diameter of Abdominal Aortic Aneurysm and Outcome of Endovascular Aneurysm Repair: Does Size Matter? A Report from EUROSTAR. Journal of Vascular Surgery, 39, 288-297. http://dx.doi.org/10.1016/j.jvs.2003.09.047
- Brewster, D.C., et al. (2006) Long-Term Outcomes after Endovascular Abdominal Aortic Aneurysm Repair. The First Decade. Annals of Surgery, 244, 426-438.
- Volodos, N.L., Shekham, V.E., Karpovich, I.P., et al. (1986) A Self-Fixing Synthetic Blood Vessel Endoprosthesis. VestnKhirImGrek, 137, 123-125.
- Parodi, J.C., Palmaz, J.C. and Barone, H.D. (1991) Transfemoral Intraluminal Graft Implantation for Abdominal Aortic Aneurysms. Annals of Vascular Surgery, 5, 491-499. http://dx.doi.org/10.1007/BF02015271
- Thomas, S.M, Gaines, P.A. and Beard, J.D. (2001) Short-Term (30-Day) Outcome of Endovascular Treatment of Abdominal Aortic Aneurysm: Results from the Prospective Registry of Endovascular Treatment of Abdominal Aortic Aneurysms (RETA). European Journal of Vascular and Endovascular Surgery, 21, 57-64. http://dx.doi.org/10.1053/ejvs.2000.1268
- Harris, P.L., et al. (1997) The Need for Clinical Trials of Endovascular Abdominal Aortic Aneurysm Stent-Graft Repair: The EUROSTAR Project. Journal of Endovascular Therapy, 4, 72-77.