Numerical Simulation of Flow Behavior in Basilar Bifurcation Aneurysms Based on 4-Dimensional Computed Tomography Angiography
- 1 Graduate School of Engineering, Chiba University, Chiba, Japan
- 2 Graduate School of Engineering, Chiba University, Chiba, Japan
- 3 Institute of Fluid Science, Tohoku University, Sendai, Japan
- 4 School of Engineering, Tokyo Institute of Technology, Yokohama, Japan
- 5 Institute of Fluid Science, Tohoku University, Sendai, Japan
- 6 Department of Neurosurgery, Mie Chuo Medical Centre, Tsu, Japan
- 7 Institute of Fluid Science, Tohoku University, Sendai, Japan
Abstract
Initiation, growth, and rupture of cerebral aneurysms are caused by hemodynamic factors. It is extensively accepted that the cerebral aneurysm wall is assumed to be rigid using computational fluid dynamics (CFD). Furthermore, fluid-structure interactions have been recently applied for simulation of an elastic cerebral aneurysm model. Herein, we examined cerebral aneurysm hemodynamics in a realistic moving boundary deformation model based on 4-dimensional computed tomographic angiography (4D-CTA) obtained by high time-resolution using numerical simulation. The aneurysm of the realistic moving deformation model based on 4D-CTA at each phase was constructed. The effect of small wall deformation on hemodynamic characteristics might be interested. So, four hemodynamic factors (wall shear stress, wall shear stress divergence, oscillatory shear index and residual residence time) were determined from the numerical simulation, and their behaviors were assessed in the basilar bifurcation aneurysm.
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