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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas…
Eun Jeoung Lee, Sung Hwa Shin, Sunghee Hyun, Sang Sun Kang
TRPV4 activity modulates cell activities including receptor trafficking and transcriptional or translational regulations. We tested its CRISPR/Cas9 scissor efficacy in HepG2 (HEK293) cell noticed that it worked well in both cell lines to eliminate TRPV4 genom…
Daisuke Funabara, Yoshinori Urakawa, Daisuke Ishikawa, Satoshi Kanoh
Troponin (Tn) is composed of three subunits (TnI, TnC and TnT) that bind Ca 2+ and regulate striated muscle contraction in vertebrates. TnT’s function has been extensively described in vertebrates, but its role has been obscure in molluscan muscles. Our previ…
Jinfen Jin, Zhongjian Li, Lanyong Zhao, Zhongjian Li
Rosa rugosa is an important garden ornamental plant which belongs to the genus Rosa of the family Rosaceae . The current wild and cultivated R. rugosa are mostly purple, pink, a small amount of white, but lack of yellow, orange and so on. Flavonoids 3’-hydrox…
Kishan Pavani Jankuti, Anusha Govindula, Rajkumar Jampala, Mohammad Arif Pasha, Aligeti Sravan Kumar, Sunayana Soorammagari, Chinnela Satish, Mahankali Naga Ganesh
The main aim of this study is to determine the anti-hyerlipidemic and anti-obesity activity of Canephora robusta in hyperlipidemia induced rats. Prepared coffee bean extract (GCE) was procured from the market which is unroasted and contains more quantity of c…
Tijani S. Abiola, Ashimolowo O. Susan, Babalola O. Olusegun
Piroxicam is commonly used as anti-inflammatory and pain relieving drug; however, its side effects include fluid retention, renal damage and heart failure. This study aimed at evaluating the nephroprotective role of different doses of the tannin-rich extract…
Sung Hwa Shin, Eun Jeoung Lee, Sunghee Hyun, Sang Sun Kang
Serum- and glucocorticoid-induced kinase 1 (SGK1) is known to have consensus sequence of phosphorylation site R-x-R-x-x-(S/T)-Φ, where Φ is any hydrophobic amino acid and arginine residues are conserved at positions −5 and −3 relative to positions…
Isao Eto
Research Aims: Obesity and type 2 diabetes are known to be associated with increased risk of various types of cancer. However, the molecular biological mechanism of how the risk of cancer is increased in obesity or type 2 diabetes is not known. The aim this r…
Fawziya A. R. Ibrahim, Marwa S. Abouelenein, Ola S. A. Sakr, Sanaa S. Ahmed, Ebtisam R. Zaher, Shaymaa E. el Feky
Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a key player in the extrinsic pathway of apoptosis; it selectively damages cancer cells through binding to its surface receptors, however, cancers can escape this pathway through e…
Tijani S. Abiola, Awaje Dorcas, O. O. Babalola
Hepatic injury has been reported to be associated with chloroquine therapy. Gomphrena celesioides has been claimed to have pleiotropic protective properties in the liver by traditional herbal practitioner but there is no scientific evidence to this claim. Thi…
Fauzun Shaona, Rubyyat Hassan, Sajib Chakraborty, Shahanaz Sultana, Jobaida Akther, AHM Nurun Nabi
This study investigated distribution of HLA alleles (HLADRB1*01, *03, *04, *07, HLA-DQB1*0201, *0301/4) in 34 healthy controls and 57 rheumatoid arthritis (RA) patients in a Bangladeshi population and correlated the genotypic frequencies with clinical paramet…
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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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