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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas…
Emer K. Phelan, Manfredi Miraula, Christopher Selleck, David L. Ollis, Gerhard Schenk, Nataša Mitić
Antibiotic resistance is one of the most significant challenges facing global healthcare. Since the 1940s, antibiotics have been used to fight infections, initially with penicillin and subsequently with various derivatives including cephalosporins, carbapenam…
S. O. Ita, E. O. Aluko, T. H. Olubobokun, U. A. Okon, A. B. Antai, E. E. Osim
The relationship between Nigerian Bonny Light crude oil (NBLCO) induced hypoglycaemia and endogenous serum insulin concentration; the role of antioxidant vitamin C or E supplementation was the focus of this study. Forty adult male Wistar rats were randomly di…
Zibin Jiang, Jinwen Chen, Cornelius E. Uboh, Mary A. Robinson, Lawrence R. Soma
Selection of proper reference genes (RGs) is an essential step needed for accurate normalization of results from genomic studies. Expression of RGs is regulated by many factors such as species, age, gender, type of tissue, the presence of disease, and the adm…
Anamaria da Silva Facina, Gil Facina, Ismael Dale Cotrim Guerreiro da Silva, Giovana Aparecida Gonçalves, Fernando Augusto de Almeida, Silvana Aparecida Alves Corrêa de Noronha, Samuel Marcos Ribeiro de Noronha, Mary Uchiyama Nakamura
Cancer is a major public health problem throughout the world. It is estimated that one third of the American population will develop the disease at some time during their lifetimes. Among these, melanoma will account for 7% of the cases. In Brazil, in 2012, i…
Nicholas J. Macedo, Catherine C. Neto, Anne M. Liberty, Tracie L. Ferreira
Antioxidants have been widely studied in various naturally occurring substances as a bioavailable cancer prevention treatment. Proanthocyanidins (PACs), which are abundant polyphenols in Early Black (EB) Cranberry ( Vaccinium macrocarpon ), are readily availa…
Hassan A. Alsokary, Mostafa A. Kamel, Sameh S. Sadek, Nermine H. Zakaria, Iman A. Abdel Fatah
Preeclampsia is a frequent disorder with reported incidence in pregnancies. In Egypt, it complicates 6%- 8% of pregnancies and reaches 15% in referral centers. The renin-angiotensin system activation during the early stages of Preeclampsia proved to be a dire…
Aleksander N. Zimnitskii, Sergey A. Bashkatov, Aleksey V. Chemeris, Renat S. Yamidanov, Vadym N. Urazbaev
Quantum-chemical calculations and in vitro experiments have demonstrated that polysaccharides are able to adsorb mononucleotides due to the formation of hydrogen bonds. The subsequent dehydration of polysaccharide-nucleotide complexes in the physiologically a…
Neetu Verma, Pradeep Kumar Burma
We introduce a homology-based recombination approach for generating a cDNA construct. This method depends on amplifying several exon fragments and their fusions by the homology-based recombination. This method provides a way to generate the cDNA sequence of a…
Chun-Feng D. Hou, Emer K. Phelan, Manfredi Miraula, David L. Ollis, Gerhard Schenk, Nataša Mitić
Metallo- β -lactamases (MBLs) are a family of Zn 2+ -dependent enzymes that have contributed strongly to the emergence and spread of antibiotic resistance. Novel members as well as variants of existing members of this family are discovered continuously, compo…
Nabil El-Halawani, Nahla Hamed, Mohamed Eldafrawi, Zeinab Mourad, Amani Sorour, Omar Ghallab
Background: MicroRNAs (miRNAs) are short non coding RNAs of ~ 21 to 23 nucleotides in length that post-transcriptionally regulate mRNA expression. Highthroughput methodologies have shown deregulated miRNA expression in an increasing number of human cancers. M…
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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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