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Chinese Medicine (CM) is an openly accessible journal published quarterly. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in Chinese medicine related problems. Manuscripts can be prepared in English or…
Yanwu Zhao, Junhui Hu, Jiang Song, Xinhong Zhao, Yanjing Shi, Yanping Jiang
The paper is proposed to explore the potential effects of Shufeng Jiedu Capsule against COVID-19. The ingredients and targets of Shufeng Jiedu Capsule were collected by the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMS…
Yanwu Zhao, Junhui Hu
Objective: To investigate the possible mechanism of Yiqing Capsules in the treatment of upper respiratory tract infection based on network pharmacology. Methods: The main active components of Yiqing Capsules were selected on TCMSP database; the targets of upp…
Pou-Kuan Leong, Hoi-Yan Leung, Wing-Man Chan, Kam-Ming Ko
“Meridian tropism” refers to the organ-specific biological action(s) produced by a Chinese herb following its oral administration, which is analogous to the concept of “bioavailability” in Western medicine. In this study, we compared the in vitro and ex vivo…
Xichen Du, Changshi Qian, Xinglin Jin
To investigate the effect of mitochondrial DNA deletion and OSW-1 on PI3K-AKT signaling pathway PCR Array in SK-Hep1 hepatocellular carcinoma cells , we prepared SK-Hep1 cells with mtDNA deletion , that is , p 0 SK Hep. Then the OSW-1 of 100 ng/L was used to…
Yingshan Zhang, Bibo Zhang
Theory of both Zangxiang ( 藏象 ) and Jingluo ( 经络 ) is useful in understanding disease. By using mathematical reasoning based on Yin Yang Wu Xing Theory in Traditional Chinese Medicine (TCM), this paper demonstrates the treatment principle: “Searching for a ro…
Hoiyan Cheung, Litai Lin, Jiawen Chen, Jianwei Zhen, Kaman Yung, Qingyu Ma, Jiaxu Chen
Background: The foundation of this acupuncture model is to solve the lack of experimental teaching model and student’s inadequate ability to identify acupoints in the teaching of acupuncture and moxibustion in traditional Chinese medicine. Methods: In this mo…
Zhijia Pan, Xiaolei Zhang, Changshi Qian, Xiaochen Liu, Xinglin Jin
Interleukin I receptor associated kinase 1 (IRAK1) is a downstream signal molecule of activated MyD88 recruitment, which can activate Fas associated death domain protein (FADD) to induce apoptosis. IRAK1 can also activate tumor necrosis factor-related factor…
Dan Ma, Wenjun Liu, Lu Wang, Xinzhu Xu, Lingzhi Wang, Huaxin Yu, Xudong Liu, Huihui Liu, Deshan Wang, Dehong Shan
Objective: Mitochondrial impairment in the skeletal muscle contributes to useless of limbs in spleen qi deficiency ; however the genesis of such impairment is not clear. Herein, PTEN-induced putative kinase 1 (PINK1)-Parkin pathway and mitophagy were studied…
Ke Chen, Liudan Chen, Qihui Huang, Aizhen Pan, Kefang Chen, Xiangping Hou, Xiaojin Xue, Jianjun Li
Objective: To investigate the mechanism of Cornus officinalis Total Glycosides (COTG) on myocardial protection, by studying effects of COTG on cardiomyocyte apoptosis induced by hypoxia/reoxygenation and calcium concentration in rats. Methods: The myocardial…
Shanlei Zhang, Changshi Qian, Xiaochen Liu, Shengjun Piao, Xinglin Jin
RAC1 is a small-molecule G protein that regulates multiple cell cycle, cytoskeletal reorganization, cell migration, and apoptosis. FADD-dependent TRAIL can promote tumor metastasis through RAC1 and PI3K, and down-regulating RAC1 expression can reduce FasL-ind…
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Chinese Medicine (CM) is an openly accessible journal published quarterly. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in Chinese medicine related problems. Manuscripts can be prepared in English or… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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