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International Journal of Clinical Medicine is a peer reviewed journal dedicated to the latest advancements of clinical medicine. The goal of this journal is to serve as a resource for dissemination of state-of-the-art research and educational material within the field of clinical medicine. All manuscripts submitted to…
T. Chase, K. E. Cham, B. E. Cham
Purpose: To establish whether Curaderm, a topical pharmacotherapy for skin cancer, irritates or sensitizes normal skin. Methods: The dermal irritation and skin sensitization toxicity of Curaderm were investigated in rabbits and guinea pigs in compliance with…
Shunling Li, Surui Liang, Weihua Xue
Objectives: To explore the main points of perioperative nursing for adult congenital heart disease with severe pulmonary arterial hypertension. Methods: A retrospective study of 13 patients with congenital heart disease and severe pulmonary arterial hypertens…
Jun Sato, Satoru Iwasa, Yoshitaka Honma, Atsuo Takashima, Natsuko Okita, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Narikazu Boku
Purpose: Several studies have shown that fluoropyrimidine plus oxaliplatin (SOX) is non-inferior to fluoropyrimidine plus cisplatin as first-line chemotherapy for advanced gastric cancer. We investigated retrospectively the choice of second-line regimen, alon…
Jing Liu, Yanwen Xu, Tingting Wu, Xia Liu, Yanhua Sun
Objective: Abnormal miRNA expression is observed in several human tumors; moreover, normal cell regulation can be disrupted by tumor-suppressive or oncogenic miRNAs. We aimed to investigate the role of miR-637 in gliomas. Methods: We assessed miR-637 expressi…
Wei Chen, Xiaoping Tan, Junwen Ye, Yan Zhang, Jinglin Liang, Meijin Huang
Objective: To retrospectively analyze the prognostic differences between LCC and RCC, and to explore the occurrence of such differences in the relevant factors. Provide clinical basis for the individualization and precise treatment of CRC. Methods: The clinic…
Shunling Li, Surui Liang, Weihua Xue
Background : Septic shock is a rapidly changing and fatal syndrome that can cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodyna…
Qian Zhao, Zhangshun Shen, Hui Guo, Jianguo Li
Clinical thinking have the uncertainty, by which there are not a few mistakes caused. So it is necessary to discuss how to deal with the uncertainty of clinical thinking, which originates from the uncertainty of the objective world, social world and medicine…
Amra Ziadi, Abdelhamid Hachimi, Raja Hazime, Imane Brahim, Brahim Admou, Fouzia Douirek, Ahmed R. El Adib, Said Younous, Abdenasser M. Samkaoui
Background: The alteration of lymphocyte subpopulations can help to predict the severity and the prognosis of severe Coronavirus disease 2019 (COVID-19). Our goal was to describe the kinetics of lymphocyte subsets, and their impact on the severity and mortali…
Marius D. Roatis, Alexandru V. Georgescu
Background : Pilonidal disease is a chronic inflammatory disease of the sacrococcygeal region that mainly affects young people. Its incidence is 26 cases per 100,000 persons. Although many techniques have been described, there is no consensus on the treatment…
Jiménez-Cohl Pedro, Aspeé Maximiliano, Vega M. Teresa, Canto Yianinna, Peña José Tomás, Bocaz Sebastián, Tapia Francisco
It is not common to start suffering from syncopes after age 50. They are mainly male patients who present causes other than vasovagal syncope, which predominates at an early age. Orthostatic hypotension is the predominant causal factor, which is attributed in…
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International Journal of Clinical Medicine is a peer reviewed journal dedicated to the latest advancements of clinical medicine. The goal of this journal is to serve as a resource for dissemination of state-of-the-art research and educational material within the field of clinical medicine. All manuscripts submitted to… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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