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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap…
Hela Slimi, Khemaïs Saïd, Younes Moussaoui, Ridha Ben Salem
Various 3,4-dihydropyrimidinones can be prepared via Biginelli reaction in aqueous media by using quaternary ammonium salts of different alkyl groups (C4 and C8) and anions (Cl - and Br - ) as catalysts. The use of quaternary ammonium salts along with longer…
Wail Al Zoubi
Schiff bases are the most widely used organic compounds. They have been shown to exhibit a broad range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Th…
Dalia Hussein Soliman
A new series of quinoxaline 1,4-di-N-oxides were synthesized and evaluated for their antibacterial and antifungal activities. The best result was demonstrated by 3-amino-N-(4-methoxyphenyl)-2-quinoxalinecarboxamide 1,4-di-N-oxide 4e , MIC (0.24 μg/ml ) agains…
Rachana Singh, Rimpa Jaiswal, Thakohari Goswami
Towards the development of potential new organic photovoltaic and optoelectronic materials, a simple route to synthesize flexibly ether linked fullerene-bis[oligo-(phenylene-alt-thiophene)] and evaluation of electrochemical, photophysical and magnetic propert…
Massimo Corsi, Marco Bonanni, Giorgio Catelani, Felicia D’Andrea, Tiziana Gragnani, Roberto Bianchini
Primary tosylates 1a - d were converted to the corresponding amino species 3a - d . Benzylamine was proved effective for the substitution of tosylates, using acetonitrile (MeCN) as the solvent of choice and citric acid to remove excess of the reagent from cru…
Abdulrahman G. Alshammari, Abdel-Rhman B. A. El-Gazzar
A new and efficient procedure has been designed for the preparation of 6-arylmethylene-amino-2-alkyl sulfonyl-pyrimidine. The first alkylthio group was introduced into the pyrimidine ring by S -alkylation. The introduction of the second one was successfully a…
Abdulrahman G. Alshammari, Abdel-Rhman B. A. El-Gazzar, Hend N. Hafez
A highly practical and efficient preparation of 6-methy-4 H -thiochromene and 7-methyl-thiochromene[2,3- d ]pyrimidine derivatives was developed via a multi-component reaction of 3-methyl-thiophenol ( 1 ), aldehydes ( 2 ), and malononitrile ( 3 ). A series of…
M. G. Veliyev, M. A. Salmanov, M. I. Shatirova, S. R. Aliyeva, L. N. Bunyatova
The methods of preparation of endiine and endiallene diols by interaction of cis-1,4-dibrombutene and cis-1,4-dichlor-rbutene with monosubstituted acetylene alcohols in presence of the catalytic systems consisting of one-iodide copper, triethylamine and K 2 С…
Yoshikazu Kimura, Daisuke Matsuura
An environmentally benign and practical preparation method for the Vilsmeier - Haack reagent (VH) has been developed by using phthaloyl dichloride with DMF in toluene or 2-chlorotoluene. Phthalic anhydride as the byproduct was recovered in high yield by simpl…
Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
The use of thallium(I) hydroxide (TlOH) as a base is known to extremely accelerate the Suzuki-Miyaura cross-coupling reaction using organoboronic acid or organoboronic acid ester as a substrate. Here, we investigated the effects of TlOH by comparing with othe…
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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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