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JBiSE is an openly accessible journal published monthly. All manuscripts must be prepared in English and are subject to a rigorous peer-review process. Generally, accepted papers will appear online within 3 weeks followed by printed hard copy. The areas covered by JBiSE include but are not limited to the following fie…
José Manuel Hermosillo-Sandoval, Luis Miguel Román-Pintos, Adolfo Daniel Rodríguez-Carrizález, Ernesto Germán Cardona-Muñoz, Fermín Paul Pacheco-Moisés, Genaro Gabriel Ortiz, Alejandra Guillermina Miranda-Díaz
Introduction: In bile duct injuries (BDI), cholestasis and cholangitis can alter the fibrinolytic system by promoting an increase of extracellular matrix depositions which favor an imbalance between metalloproteinases (MMPs) and their tissue inhibitors (TIMPs…
Hana Tuby, Tali Yaakobi, Lidya Maltz, Yaakov Delarea, Orit Sagi-Assif, Uri Oron
In this study, we investigated the hypothesis that photobiostimulation by low-energy laser therapy (LLLT) applied to the bone marrow (BM) of myocardial infarcted rats may attenuate the scarring processes that follow myocardial infarction (MI). Wistar rats und…
Lucia Machová Urdzíková, Petr Lesný, Eva Syková, Pavla Jendelová
Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are…
Junwei Hu, Shuang Dong, Qinqin Wang, Yicheng Jian, Lijuan Hu, Lijing Wang, Yi He, Genmei Yang, Jinjun Wang, Wujun Xiong
AIM: To investigate the effects of oxymatrine on the gene expression profile of hepatic stellate cell (HSC) and provide novel insights into the mechanism of oxymatrine against hepatic fibrosis. Methods: HSC was isolated from normal SD by in situ perfusion of…
Theodore Dassios, Anna Katelari, Stavros Doudounakis, Gabriel Dimitriou
Introduction: Respiratory muscle strength can be assessed by static mouth measurements of maximal inspiratory pressure (Pi max ) and maximal expiratory pressure (Pe max ). Impaired respiratory muscle strength is common in neuromuscular and obstructive pulmona…
Sam Straw, Paul Ko Ferrigno, Qifeng Song, Darren Tomlinson, Francesco Del Galdo
Background: Nine proteins were identified as putative profibrotic biomarkers in systemic sclerosis (SSc) and an unrelated fibrotic disease in a previously published proteomic study. As the majority of these proteins were orphans of commercially available anti…
Zheng Wang, Xiaoju Zhang, Yi Kang, Yanli Zeng, Hongmei Liu, Xiaoqian Chen, Lijun Ma
Idiopathic pulmonary fibrosis (IPF) is characterized by exuberant apoptosis and inadequate regeneration of lung parenchyma cells. Intratracheal alveolar type II epithelial cell instillation alleviates lung inflammation and fibrosis. Resident lung epithelial s…
Naoki Hotta
The development of fibrosis in hepatitis C patients is associated with increased rates of liver cancer. Assessing hepatic fibrosis during interferon treatment for chronic hepatitis C is thus an important factor in treatment planning. Complications such as ble…
Richard G. DiScipio, Sophia K. Khaldoyanidi, Rosita Moya-Castro, Ingrid U. Schraufstatter
A major portion of the beneficial effect of mesenchymal stem cells (MSC) is due to the production of trophic and angiogenic factors by these cells, and one of the efforts to improve the therapeutic efficacy of these cells lies in enhancing this capacity. Sinc…
Nguyen Thi-Hiep, Dao Van Hoa, Vo Van Toi
A novel injectable hydrogel that was synthesized by in situ crosslinking of hyaluronan and polyvinyl phosphonic acid was proposed in this study. Fourier transform infrared spectrum (FT-IR) analysis, scanning electron microscope (SEM), pH measurement, and biod…
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JBiSE is an openly accessible journal published monthly. All manuscripts must be prepared in English and are subject to a rigorous peer-review process. Generally, accepted papers will appear online within 3 weeks followed by printed hard copy. The areas covered by JBiSE include but are not limited to the following fie… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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