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Journal of Biophysical Chemistry (JBPC) is an international journal dedicated to the latest advancements in biophysical chemistry. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas o…
Hemendra J. Vekaria, Ratna Prabha Chivukula
Thiols play very important role in the intracellular redox homeostasis. Imbalance in the redox status leads to changes in the intracellular metabolism including respiration. Thiol stress, a reductive type of stress can also cause redox imbalance. When Gram-po…
Kiyoshi Takahashi, Kyohei Oyama, Hironori Motoshige, Koichi Sakurai
Hydrogen peroxide (H 2 O 2 ) induces the hypertrophy in cultured H9c2 cardiomyocytes and cell death in glutathione (GSH)-depleted H9c2 cells. In the present study, we observed that pretreatment with a serine protease inhibitor, N-a-tosyl-L-lysine chloromethyl…
Kazushige Yokoyama, Andrew D. Fisher, Amanda R. Amori, Daniel R. Welchons, Ruel E. McKnight
Thermodynamic properties of complexes of Con ?go Red (CR) dye with amyloid ? (A?) peptides were studied by both absorption spectroscopy and isothermal titration calorimetry (ITC). Based on the absorption spectrum for the formation of CRAβ complexes in phospha…
Atanu Singha Roy, Debi Ranjan Tripathy, Angshuman Chatterjee, Swagata Dasgupta
The interaction of naringin with bovine serum albumin has been performed using fluorescence, circular dichroism and fourier transform infrared spectroscopy in 20 mM phosphate buffer of pH 7.0 as well as molecular docking studies. The changes in enthalpy (ΔH°)…
Young-Sik Park, No-Soo Park, Jun-Bong Seo, Soo-Kyoung Bae, You-Kwang kim, Ki-Soo Seong, Young-Jun Kim, Ju-Won Park, Joung-Moung Shin, Young-Chan Jeon, In-Kyo Chung, Moon-Kyoung Bae, Hye-Ock Jang, Il Yun
The aim of this study was to provide a basis for examining the molecular mechanism for the pharmacological action of ethanol. We studied di¬myristoyl¬phosphatidylethanol (DMPEt)’s effects on specific locations of n-(9-anthroyloxy) palmitic acid or stearic aci…
Manami Nishizawa, Kazuhisa Nishizawa
How membrane curvature influences lipid distribution is under intensive research. In this short report, after a brief review of recent studies, the results of our coarse-grained (CG) molecular dynamics simulations of membranes with “hemifused ribbons” geometr…
Srinivasa Rao Karumuri, A. S. R. Prasad, Nirmal Kumar Sarkar, Joydeep Choudhury, Ramendu Bhattacharjee
We introduce an algebraic model to vibrations of polyatomic Bio-molecules and present, as an example, the vibrational analysis of Cm-H, Cm-C, Cm-D, Cb-Cb, pyrrol breathing and Cb-C, stretching modes of Metalloporphyrins and its substituted forms. The excited…
Jai Mittal, Gayathri Ravitchandirane, Tapan K. Chaudhuri, Pratima Chaudhuri
The design of any antagonist or inhibitor for any enzyme requires the knowledge of structure- function relationship of the protein and the optimum conformational states for maximum and minimum activities. Furthermore, designing of the inhibitors or drugs agai…
Shweta Joshi, Alok Ranjan Singh, Uzma Saqib, Prakash Chandra Misra, Mohammad Imran Siddiqi, Jitendra Kumar Saxena
Transketolase, the most critical enzyme of the non-oxidative branch of the pentose phosphate pathway, has been reported as a novel target in Plasmodium falciparum as it has least homology with the human host. Homology model of P. falciparum transketolase (PfT…
Natallia V. Grib, Dmitry A. Ryndyk, Rafael Gutiérrez, Gianaurelio Cuniberti
Using a tight-binding model, we investigate the influence of intra- and interstand coupling parameters on the charge transport properties in a G-(T)j-GGG DNA sequence and its (G:C)-(T:A)j-(G:C)3 duplex attached to four electrodes. Dependences of the transmiss…
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Journal of Biophysical Chemistry (JBPC) is an international journal dedicated to the latest advancements in biophysical chemistry. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas o… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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