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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Domenico Mastrangelo, Lauretta Massai, Giuseppe Fioritoni, Antonio Iacone, Paolo Di Bartolomeo, Patrizia Accorsi, Tiziana Bonfini, Michela Muscettola, Giovanni Grasso
Arsenic Trioxide (ATO) is widely acknowledged as the treatment of choice for Acute Promyelocytic Leukemia (APL). It is a “two-sided” drug since it can induce differentiation or kill APL and other tumor cells according to the dosage. Part of the cytotoxic effe…
Mario Gosalvez
The author, concisely and generically, proposes experimental testing on suitable laboratory animals, in state-of-the-art international centers endowed with cancer reversal experimental techniques. Using mild carcinogens to induce more or less benign growths c…
Mohammad M. Abd-Alhaseeb, Sawsan A. Zaitone, Soad H. Abou-El-Ela, Yasser M. Moustafa
Sorafenib was the first multikinase inhibitor to be approved for use in metastatic renal cell carcinoma. Olmesartan medoxomil used in treatment of hypertension and was reported to inhibit angiogenesis in several models. The present study was designed to asses…
Vinayak Khattar, Jaideep V. Thottassery
Deregulation of the cell cycle results in loss of normal control mechanisms that prevent aberrant cell proliferation and cancer progression. Regulation of the cell cycle is a highly complex process with many layers of control. One of these mechanisms involves…
Tadashi Kayashima, Masafumi Nakamura, Kenoki Ohuchida, Syunichi Takahata, Kohei Nakata, Naoki Ikenaga, Lin Cui, Shingo Kozono, Kazuhiro Mizumoto, Masao Tanaka
Background/Purpose : A recent genome-wide association study (PanScan) identified significant association between the ABO gene locus and the risk of pancreatic cancer. The aim of this study was to analyze survival of pancreatic cancer patients who underwent su…
Zoltán Berger, Maria Ester Bufadel Godoy, Alex Navarro Reveco
Endoscopic methods are widely used in the diagnosis and palliative treatment of pancreatic cancer. The most sensitive method in early diagnosis is endosonography (EUS) which can also provide histological diagnosis. Diagnostic ERCP became a rather rare procedu…
Manuela Pennisi, Giuseppe Chisari, Marco Vacante, Francesco Lucca, Salvatore Spitaleri, Giulia Malaguarnera, Giuseppe Grosso, Filippo Drago, Vito Catania, Alfredo Consoli, Mariano Malaguarnera
Background: Since the survival rates of cancer have increased considerably, the long-term side effects of cancer and cancer-related treatments may impact survivors’ capability to regain normal lives. The aim of this study was to evaluate the effects of the br…
Sacha Satram-Hoang, Carolina Reyes, Khang Q. Hoang, Faiyaz Momin, Sandra Skettino
Introduction: Chronic lymphocytic leukemia (CLL) is a disease of the elderly. Elderly patients often have increased comorbidity burden and loss of organ reserve that may impact their ability to tolerate cancer therapy. We described realworld characteristics o…
Hartmut Kirchner, Axel Heidenreich, Bernhard Brehmer
Renal cell carcinoma (RCC) is the 10 th leading cause of deaths from cancer in the Western world. During the last two decades this type of malignancy was difficult to treat with limited treatment options using cytokines like interferon alpha (IFN) or interleu…
José Barbosa, Silvestre Carneiro, John Preto, Hugo Sousa, André Pinho, Costa Maia
Main Goals: Evaluation and comparison of short-term results of totally laparoscopic gastrectomy performed for gastric carcinoma in two groups of patients: older and younger than eighty years. Material and Methods: From 1st January 2011 to 31st October 2012, w…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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