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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
E. P. Slater, J. Waldmann, C. López, E. Matthäi, V. Fendrich, D. K. Bartsch
Prognosis in well-differentiated neuroendocrine carcinomas varies considerably and therapeutic targets for metastatic disease are urgently needed. cDNA microarray studies in our laboratory revealed a significantly lower expression level of the Noxa -gene in h…
Helmut Oettle
Presently, many questions exist about what the optimal regimen comprises for all stages and treatment settings for pancreatic cancer. Since the CONKO-001 trial, adjuvant therapy following resection has become standard of care; however, outcomes are poor, with…
Dissanayake Thusitha, Arze Elizabeth, Rogers Mailien
Two different immunohistochemical types suggestive of Large Cell Neuroendocrine (NE) carcinoma and Adenoc a rc i noma in a patient with known diffusely metastatic, hormone refractory prostate carcinoma are rarit ies . Interestingly, our patient had documented…
Nandini Dey, Yuliang Sun, Brian Leyland-Jones, Pradip De
Patient derived xenograft (PDX) is defined as a growth of patients’ tumor in the xenograft setting. The evolution of cancer model in animal has a century old history. The most single reason that exerted the pressure on the traditional animal model of cancer t…
Maria Del Carmen Garcia Molina Wolgien, Ismael Dale Cotrim Guerreiro da Silva, Afonso Celso Pinto Nazário, Clovis Riyuchi Nakaie, Silvana Aparecida Alves Corrêa de Noronha, Samuel Marcos Ribeiro de Noronha, Gil Facina
Background: Breast cancer is the most common type of cancer among women. Diagnosed and treated timely , p a tients may have good prognostics. In Brazil, in 2012, the estimate of new cases was 52,680 and the number of registered deaths in 201 2 was 12,852. The…
Maurice Matter, Sebastien Romy, Ariane Boubaker, Olivier Michielin, Nicolas Demartines
Objective: Sentinel lymph node biopsy (SLNB) is a validated staging technique for breast carcinoma. Some women are exposed to have a second SLNB due to breast cancer recurrence or a second neoplasia (breast or other). Due to modified anatomy, it has been clai…
Mohamed Mahmoud, Tarek Shouman, Hesham Elhosseny, Mona Aboelenin, Mohamed Amin
Purpose: The aim of the present study is to compare between the use of post-operative concurrent chemotherapy and radiotherapy alone on survival for patients with high risk oral cavity tumors at the National cancer Institute of Egypt, undergoing surgery and r…
Mahtab Ordooei, Mojgan Karimi-Zarchi, Golnaz Malekzadeh, Mansour Moghimi
Isosexual precocious puberty in girls has several etiologies. Juvenile granulose cell tumor is one of the rarest causes that only stands for 1.5% of ovarian cancers. This tumor mostly encounters in first 2 decades of life. This paper is a report of an 8-year-…
Goki Shindo, Takayoshi Endo, Masamitsu Onda, Shigenori Goto, Yoju Miyamoto, Toru Kaneko
Background: The importance of immunotherapy in cancer treatment has been increased owing to its non-toxicity and application to personalized medicine. However, precise estimation indices of immunotherapy have yet to be established. To determine effective eval…
Ayse Arslan, Halit Demir, Harun Arslan
Hepatocellular carcinoma (HCC) is among most common terminal cancer types in the world. Primary etiological factors include cirrhosis, hepatitis, aflatoxin and alcohol. The current study was conducted to determine cytosolic erythrocyte carbonic anhydrase and…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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