Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Angel Ferrández, Sonia Mostacero, Angel Lanas
Gastric cancer is the most common cancer worldwide and it is often diagnosed in an advanced stage. In countries where screening endoscopy is performed widely, early detection is possible. In fact, early gastric cancer incidence is increasing during the last y…
Ami Karkar, Sachin Patil, Ronald S. Chamberlain
Introduction: Gastric cancer is the 4 th most common malignancy and second leading cause of cancer-related death worldwide, both its incidence and mortality have decreased over the past 70 years. Advancing life expectancy, as well as subtle change in the type…
Tomoya Sudo, Ryunosuke Kogo, Naohiro Nishida, Keisuke Takahahi, Genta Sawada, Masahisa Ishibashi, Junji Kurashige, Ryutaro Uchi, Tae Matsumura, Hiroki Ueo, Kousuke Mima, Sayuri Akiyoshi, Keishi Sugimachi, Kouhei Shibata, Hiromasa Fujita, Kazuo Shirouzu, Masaki Mori, Koshi Mimori
Loss of Heterozygosity (LOH) is commonly considered to be one of a reason when some genes lose their function. Numbers of tumor suppressor genes are existing on the LOH lesion and chromosome 16q24 had been reported as a LOH region in gastric cancer. Little is…
Khawaja Shakeel Ahmed, Basheer Madompoyil, Anghesom Ambesajir Ghebremedhin, John Issac, Janak Dulari Ahi, Aleem Ahmed Khan, Santosh Kumar Tiwari
Introduction : H. pylori is a primary pathogen isolated by Warren and Marshall in 1983. They called it as Campylobacter Pylori and in 1989 Goodwin et al . renamed it as Helicobacter pylori. Helicobacter pylorus is one of the responsible factors for causing ga…
Takashi Kosaka, Masaki Endo, Yousuke Toya, Tomomi Mizutani, Yukito Abiko, Norihiko Kudara, Masaaki Inomata, Toshimi Chiba, Yasuhiro Takikawa, Kazuyuki Suzuki, Tamotsu Sugai
Aim: The aim of this study was to examine the safety and efficacy of endoscopic submucosal dissection (ESD) for early gastric cancer based on approximately 10 years’ experience. Methods: Endoscopic submucosal dissection was performed in 1272 patients with ear…
Takahisa Suzuki, Kazuaki Tanabe, Dang Thuc Anh Vu, Toshihiro Misumi, Nobuaki Fujikuni, Noriaki Tokumoto, Hideki Ohdan
Background: This study aimed to determine the safety and effectiveness of laparoscopy-assisted distal gastrectomy (LADG) after ESD. Methods: We reviewed patients with gastric cancer who underwent distal gastrectomy after non-curative ESD from May 2000 to July…
Chunhui Lu, Shiwen Chen, Feng Xu, Yiwen Chen, Qing Zhang, Yong Li
Purpose : The chemokine receptors CCR7 and CXCR4 have been shown to play an important role in cancer invasion and metastasis . This study was aimed to investigate CCR7 and CXCR4 expressions and evaluate the association between their expressions and the clinic…
Hongwei Xu, Guangda Xu, Qingyao Zhang, Gang Qu, Yanmin Yu, Yangsen Jiang
Background : Runt domain transcription factor 3 (Runx3) is a putative tumor suppressor in human neoplasia. Previous researches suggested that a lack of Runx3 function contributed to human gastric carcinogenesis, however, it is not clear whether Runx3 is close…
Edaise Maria da Silva, J. H. T. G. Fregnani, Ghyslaine Martel, Wilson Luiz Costa Jr., Felipe José Fernández Coimbra, Maria Isabel Waddington Achatz, Pierre Hainaut, Fernando Augusto Soares
Early gastric carcinomas may develop with a molecular profile differing from sporadic carcinomas occurring at a later age. In this study, we analyzed a retrospective series of 88 patients with gastric adenocarcinoma diagnosed before the age of 45 years for th…
Kouichi Nonaka, Hiroto Kita
The field of endoscopy has progressed markedly and become widespread in recent years, and the role of minimally invasive endoscopic treatment has become increasingly more important with the increase in the number of patients in whom gastric cancer is detected…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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