Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Sara Terenzi, Daniela di Cristino, Alessandra Murgia, Dania Janniello, Elisabetta Ponti, Barbara Tolu, Sara Cicchetti, Riccardo Santoni
Purpose: To report a retro-orbital localization of Multiple Myeloma (MM) describing its treatment and clinical result. Case report: A 50-years-old male patient with Magnetic Resonance Imaging (MRI) evidence of a retro-orbital mass with exophthalmos, due to th…
Sherif A. Raafat, Emmad E. Habib, Ashraf M. Maurice
Purpose: To evaluate the efficacy of concurrent intravenous cisplatin versus oral capecitabine with radical radiotherapy in locally advanced squamous cell carcinoma of the head and neck. Materials and methods: Between January 2007 and December 2009, 60 patien…
Naohiro Sekiguch, Naoki Takezako, Miyuki Wagatsuma, Chen A. Kunihiro, Akihisa Nagata, Ichiro Fukuda, Satoshi Noto, Ikuo Saito, Kazuaki Yamada, Akiyoshi Miwa
Waldenstr?m macroglobulinemia (WM) is a rare lymphoid malignancy. Many studies, including clinicopathological, cytogenetic, gene expression profile, and therapy studies have been reported from the US and Europe, although only a few reports are available from…
Ferga C. Gleeson, Allison J. Clapp, Robert C. Murphy, Jonathan E. Clain, Prasad G. Iyer, Elizabeth Rajan, Mark D. Topazian, Kenneth K. Wang, Michael J. Levy
Introduction: In the setting of an extra-adrenal malignancy, it is a recognized clinical challenge to try and distinguish a benign adrenal mass from a metastatic deposit. Current non-invasive diagnostic tools for adrenal gland evaluation include CT, MRI, PET…
Edén A. Alanís-Reyes, José L. Hernández-Cruz, Jesús S. Cepeda, Camila Castro, Hugo Terashima-Marín, Santiago E. Conant-Pablos
Breast cancer is one of the most common and deadliest types of cancer among women and early detection is of major importance to decrease mortality rates. Microcalcification clusters and masses are two major indicators of malignancy in the early stages of this…
Tamara Jane Johnson, Zafar Uddin Khan, Sadaf Mustafa, Kushal Desai, Naser Uddin Höti
Prostate specific conditionally replicating adenoviruses (CRAd) are made by placing a tissue specific promoter upstream of one or more of the viral genes required for replication (e.g., E1A, E1B). However, one major problem associated with these vectors is th…
Rajiv Samant, Michael Scopazzi, Kathy Carty
Purpose: To assess clinical outcomes after using IG-IMRT for palliation among patients with advanced cancers. Methods: Patients with advanced and/or metastatic cancers were treated on our Tomo-PAL (Tomotherapy?-Planning and Administration Linked) protocol usi…
Flipo Bernard, Clough Krishna, Nos Claude, Miramand Bernard, Michel Cecile, Houvenaeghel Gilles, Meurette Jacques, Alfonsi Jean-Pierre
Purpose: There are still un-responded questions concerning the type of and the timing of axillary procedures that has to be performed in association with neoadjuvant chemotherapy. Methods: We led a prospective, multicentric, non-randomized study to evaluate t…
Sivatharsiny Thavarajah, Frank Weber
Purpose: The incidence of hyperplastic thyroid nodular disease has been consistently rising over the last decades. In addition, unsuspected papillary thyroid carcinoma (PTC) can be found in up to 34% of patients operated for benign thyroid lesions. PTC tends…
Masanori Hotchi, Hiroshi Okitsu, Murato Miura, Madoka Hamada, Yasuhide Sonaka, Yoh Fukuda, Tsutomu Ando, Shinji Kuratate
Background: Preoperative chemoradiotherapy (CRT) with 5-FU has been widely used to improve local control of disease and to preserve anal sphincter in the treatment of rectal cancer. UFT and S-1 as oral dihydropyrimidine dehydrogenase (DPD)-inhibitory fluoropy…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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