Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Shogo Kobayashi, Atsushi Miyamoto, Junzo Shimizu, Masaki Kashiwazaki, Yutaka Takeda, Shigeyuki Ueshima, Yongkook Kim, Toru Kitagawa, Keizo Dono, Masaki Mori, Yuichiro Doki, Hiroaki Nagano
Background: Surgery for biliary tract cancer, including pancreatoduodenectomy and major hepatectomy, is too aggressive and does not allow postoperative gemcitabine to be administered by the usual dosage protocol. We hypothesized that the feasibility of 3-week…
Rossella Di Franco, Mariagrazia Calvanese, Mariagrazia Cuomo, Roberto Manzo, Paola Murino, Salvatore Cappabianca, Vincenzo Ravo
Background: Advanced cancers frequently metastasize to bone, and the presence of bone metastases is the most common cause of cancer-related pain. Pain management requires a multidisciplinary approach that involves the use of analgesics, bisphosphonates, radio…
Makiko Shimizu, Kazuma Kiyotani, Hideo Kunitoh, Tetsuya Kamataki, Hiroshi Yamazaki
Recent genome-wide association studies have identified lung cancer susceptibility loci, such as chromosome 5p15 (telomerase reverse transcriptase, TERT and cleft lip and palate transmembrane protein 1-like, CLPTM1L), 15q25 (nicotinic cholinergic receptor α, C…
Laurent Sulpice, Emanuele D’Errico, Alexis Arnaud, Michel Rayar, Karim Boudjema, Bernard Meunier
Background: Small bowel metastases of lung adenocarcinoma represent a rare clinical entity, often diagnosed after complications due to obstruction, bleeding or bowel perforation. Case Report: We report a case of ileal metastasis discovered during an intestina…
Armin Kamyab, Michael J. Jacobs
Introduction: Renal cell carcinoma (RCC) is generally divided into clear cell, papillary, and chromophobe subtypes. Clear cell papillary RCC is a recently described subtype. Case report: We report the case of a 42 year old female who was found on computed tom…
Cheng-Bo Han, Jie-Tao Ma, Fan Li, Hua-Wei Zou
The implementation of individualized targeted therapy for metastatic colorectal cancer (mCRC), in addition to standard chemotherapeutic regimens, currently is a topic under debate. Approximately 35% - 45% of mCRC patients exhibit mutated KRAS, which is consid…
Saratchandran A. Divakaran, K. M. Sreekanth, K. V. Rao, Cherupally Krishnan Krishnan Nair
D-Aminoacid oxidase (DAO) was isolated from fresh porcine kidney; its cytotoxic potential was studied under in vitro and in vivo conditions. The isolated DAO was complexed with Fe<sub>2</sub>O<sub>3</sub> nanoparticles and its potential as an oxidation therap…
Rana Jahanban Esfahlan, Nosratollah Zarghami, Μohammad Rahmati-Yamchi, Amir Monfaredan, Samira Valiyari, Ali Jahanban Esfahlan, Raziallah Jafari Jozani, Morteza Gojazadeh, Fereidoun Mamaghani, Majid Mobasseri
Background: While the role of adipocyte-derived hormones in breast cancer pathogenesis well studied, it is speculated that there is a crosstalk between adipocytokines and Esterogen receptor(ER) signaling. To test this hypothesis we evaluate the possible corre…
Dong-Ping Jiang, Jun Yang, Hui-Feng Yuan, Yu-Quan Wu, Pei-Yong Qiu, Guang-Zhou Lu, Qing-Yong Chen
Previous study has demonstrated that the peripheral blood CD44 expression level is related with the clinical stage and lymph node metastasis of lung cancer. The present comment was to investigate the relationship between the peripheral blood CD44 expression l…
Amel Abd Allah Hashim, Mahmoud Youns, Ahmed Abd Al-rahman Soltan, Sahar Abd El-mohsen Ali
Bladder carcinoma is the foremost oncologic problem among males in Egypt. Here, we evaluated the possible diagnostic value of the urinary Nuclear Matrix Protein-22 “NMP-22” and Telomerase Reverse Transcriptase “hTERT” among histological subtypes of bladder ca…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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