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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Ahmed Elhemaly, Mahmoud Hammad, Mohamed Saad Zaghloul, 1 1, Maged Elshafie, 1 1, Naglaa Elkinaae, 1 1, Mohamed Khaled, Alaa El-Haddad
High-risk neuroblastoma still has poor survival outcome. Improvement of outcome is attributed to the consolidation of chemotherapy by autologous bone marrow transplant. Further improvement of the outcome by tandem autologous transplant is followed by immune t…
Maha L. Zamzam
Background : Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide as well as in Egypt where it constitutes a significant public health problem. HCC is the third most common cause of death from cancer and chronic infection with H…
Ali Zedan, Anwar Tawfik, Ebrahim Aboeleupn, Asmaa Salah, Aiat Morsy
Background: The intersphincteric resection the most extreme form of a sphincter-preserving alternative for the abdominoperineal resection. Aim of the Work: We investigated oncological, functional outcomes and morbidity after ISR. Methods: This retrospective s…
Ming-Bo Huang, Meng Xia, Zhao Gao, Hu Zhou, Min Liu, Shan Huang, Rong Zhen, Jennifer Y. Wu, William W. Roth, Vincent C. Bond, Jian Xiao, Jing Leng
Detection of circulating tumor-specific DNA, RNA or proteins can be difficult due to relative scarcity. Exosome s are extracellular vesicles, 30 - 150 nm in diameter derived from fusion of multivesicular bodies with the plasma membrane. They are composed of a…
Aiat Morsy, Sara H. Hammouda, Samir Shehata, Ali Zedan
Background : Adjuvant radiotherapy has increased disease - free and overall survival rates in breast cancer. Conventional ly fractionated radiotherapy delivers 50 Gy over 5 weeks which is the standard approach. A shorter duration of hypofractionated radiother…
Amal Zidan, Alaa Omran, Rania Ghonaim, Fouad Abu-Taleb, Tarek Elgohary
Background: Vitamin D regulates many aspects of cellular growth and differentiation in normal and cancer cells. There is growing evidence for both serum vitamin D level and VDR gene polymorphism as prognostic factors in hematologic malignancies. Aim of this w…
Sara Khodahemmati, Maliha Gaffar, Jintao Li, Yangjunqi Wang, Xiaoli Wang, Zhixiang Zhou, Yi Zeng
The development of esophageal cancer accompanied by the presence of human papillomavirus (HPV) DNA into the host genome. By evaluating the expression of this virus for tumor cell origin and also their cell grows and migrations, we examined esophageal cancer c…
Ieong Chon Man, Kong Soi Chao, Cheng Fai
Inflammatory myofibroblastic tumor (IMT) is a special type of mesenchymal tumors. The tumors can occur all over the body. The most common organs involved were lung, followed by mesentery, omentum, retroperitoneum , and pelvic cavity. But it occurs very rarely…
Yangjunqi Wang, Jintao Li, Fan Li, Shuying Li, Rugang Zhong
Human papillomavirus is an important cancer factor in many cancers. E6E7 is the important viral oncogene and plays an important role. It is known that its function is to regulate p53 and pRb. In this paper, in situ detection was performed to determine the int…
Alberto Olaya-Vargas, Iván Castorena-Villa, Martin Pérez-García, Gerardo Lopéz-Hernández, Nideshda Ramírez-Uribe, Haydeé Salazar-Rosales
Background: Acute graft-versus-host disease (aGVHD) is the most frequent and severe complication after allogeneic hematopoietic stem cell transplantation (HSCT). Objective: To determine if a history of prior infection in the allogeneic HSTC recipient is a ris…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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