Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Michiyo Ando, Hiroko Kukihara, Mayumi Yamamoto, Yasuyoshi Ninosaka, Naoyuki Saito
The prime aim of this study was to find a psychological process model of patients with terminally ill in home hospice investigating the contents of a narrative, and the secondary aim was to create a narrative approach program for nurses. Ten patients narrated…
Hongtao Zhou, Xinping Chen, Shuping Chen, Junhong Cai, Jiye Zhang, Shengmiao Fu
Background: To explore the impact of pU6-based tandem survivin and CDK1-specific short hairpin RNA on the biological behaviors of CNE-2 nasopharyngeal carcinoma cells in vitro and in vivo . Patients and Methods: The vectors of pU6-survivin shRNA , pU6-CDK1 sh…
Ghada Ezzat Eladawei
Background and Objective: There is marked controversy regarding optimal management patients with stage IB grade III endometrial carcinoma. The present study analyzes the current practices regarding adjuvant radiation therapy for those patients in our institut…
Yakira David, Lorenzo Ottaviano, Jihye Park, Sadat Iqbal, Michelle Likhtshteyn, Samir Kumar, Helen Lyo, Ayanna E. Lewis, Brandon E. Lung, Jesse T. Frye, Li Huang, Ellen Li, Jie Yang, Laura Martello, Shivakumar Vignesh, Joshua D. Miller, Michele Follen, Evan B. Grossman
Background and Aims: The incidence and mortality of colorectal cancer is persistently highest in Black/African-Americans in the United States. While access to care, barriers to screening, and poverty might explain these findings, there in increased interest i…
Christina Schroeder, Rita Engenhart-Cabillic, Sven Kirschner, Eyck Blank, André Buchali
Purpose: In this analysis we focused on the correlation of patients’ lung function (PFT) data and lung density changes (ΔHU) detected in follow - up CTs. Material and Methods: PFT and lung function data were available for 58 patients 12 weeks and 47 patients…
Abdelbaset Mohamed Elasbali, Elyasa Mustafa Elfakia Mohammed, Ziad Alonzi, Haya Ali Atshan Al-Ruwaili, Amierah Hail Alsharari, Abdulrazaq Alshammari, Ali Saad Almansour, Abdulwahab Abdulrahman Alsaman, Hussain Gadelkarim Ahmed
Background: The incidence of breast cancer is increasing in Saudi Arabia, chiefly in distant provinces with cases assigning advanced stages of the disease. This study aimed to evaluate the level of knowledge towards external exposure related to breast cancer…
Onur Eroglu, 1 1, Merve Celen
The aim of this study is to investigate the anti-proliferative effects of Zebularine on caspase-3 and 9 genes by methylation and protein expression on SKBR3 cells. The SKBR3 cells were treated with Zebularine at different concentrations (0 - 140 μM) for 24 -…
Onur Eroğlu, Büşra Sevim
Background and Aim: In this study, it was aimed to examine the cytotoxic effect of temozolomide (TMZ) treatment, on MCF-7 and SKBR3 cell lines, to study the methylation levels of MGMT gene expression and gene promoter region. Methods: The MTT test was perform…
Tarek Elgohary, Fouad Abu-Taleb, Rania Ghonaim
Background: Acute myeloid leukemia is a heterogeneous hematologic malignancy associated with gene mutations, chromosomal rearrangements, deregulation of gene expression and epigenetic modifications. The treatment outcome of AML is highly variable signifying t…
Yasutake Uchima, Naoki Aomatsu, Takuma Okada, Hironari Miyamoto, Gen Tsujio, Shigeaki Kurihara, Toshiki Hirakawa, Takehiko Iwauchi, Junya Morimoto, Kazuhiro Takeuchi
Background: Teratomas are a type of germ cell tumor, which are mostly benign, and dominative in adult females. Sacococcygeal teratomas are usually found in newborns or children, and can be detected prenatally; they are exceedingly rare in adults. We reported…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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