Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Kirsten H. Walen
The objective was to gain proof of genome damage-repair induced mitotic slippage process (MSP) to 4n-diplochromosome skewed division-system, earlier suggested to have “cancer-deciding” consequences. Our damage-model showed two succeeding phases : molecular mu…
Mikhail N. Shapetska, Evelina V. Krupnova, Alena P. Mikhalenka, Natalia V. Chebotareva, Anna N. Shchayuk, Svetlana G. Pashkevich, Alexander V. Prokhorov
The article presented the results of comparison of polymorphic variants of the genes GSTM1, GSTT1, GSTP1 and clinical manifestations of non-small cell lung carcinoma. The association of the genotype GSTT1 (del) with the risk of developing squamous cell lung c…
Kouassi Kouamé Konan Yvon, Touré Moctar, Séka Evrard Narcisse, Oumou Kimso, Traoré Kadjatou, Odo Bitti Addé, Traoré Asmaho Danielle, Kagambega Arsène Gaëtan, Adoubi Innocent
Objective: Contribute to improving care for prostate cancer patients in Cote d ’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and Method: It was a retro and prospective st…
Fatma M. F. Akl, Ashraf Khater
Background & Objective: Hypofractionation has been used in curative setting in breast conservative surgery, but still no adequate information about its application in the adjuvant setting after mastectomy in breast cancer patients. The aim of this trial was t…
Ghada Ezzat Eladawei, Rasha Mohamed Abdellatif, Sheref Mohamed El-Taher
Background and Objective: Based on retrospective trials, most progression sites after first line systemic therapy for metastatic non small cell lung cancer (NSCLC) were the primary disease sites rather than new sites. Therefore we conducted phase II randomize…
Juan Li, Zhenling Duan, Ma Jing, Xiaotao Jing, Li Bian
Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. We report a very rare case with Müllerian adenosarcoma arising fr…
Amal Rayan, Abbas Ahmed M. Ashraf, Hebat Allah M. Bakri
Double primary malignancies could be divided into two categories, depending on the interval between tumor diagnoses . A secondary malignancy could be defined as a new cancer that has occurred as a result of previous treatment with radiation or chemotherapy .…
Badawy M. Ahmed, Ebrahim Aboeleuon, Ahmed M. Abdel-Rahim, Osama M. Abd Elbadee
Background: Uret e rosigmoidostomy was the first form of continent urinary diversion and had broad popularity during the first half of the 20th century. Primary enthusiasm was followed by disappointment when serious problems such as pyelonephritis, electrolyt…
Amen Hamdy Zaky Aly, Ahmed EL Sayed Mohammed Khalifa, Esraa Abdallah Abdelkariem Gadallah
Background and Objectives: Chronic myeloid leukemia (CML) accounts for approximately 15% of newly diagnosed cases of leukemia in adults. In this study, the efficacy of nilotinib at 400 mg BID is compared with imatinib at 400 mg BID in CML patients with subopt…
Mohammad Nezami, Steve Hager
Since the discovery of tyrosine kinase inhibitors in treatment of lung cancer harboring such actionable targets, many lives have been prolonged. To the same extent, same group of patients have failed to benefit from this category of drugs, in long run, either…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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