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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Thomas H. Cartwright, Lonnie K. Wen, Robyn K. Harrell, Patricia S. Fox, Janet L. Espirito, Ed Wang
Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the third leading cause of cancer deaths in the United States. The goal of this study was to understand treatment patterns, biomarker testing practices, treatment adherence,…
Ketevani Kankava, Alexi Baidoshvili, Eltjo Schutter, Sytske Van der Meer, David Makaridze
This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. Diagnostic curetting and biopsy were perfor…
Adel Gabr, T. M. Elsaba, Khalid Razek, Shaima Tamam, Haisam Atta
Background: Colorectal cancer (CRC) ranks as the third most common cancer and the third most killing cancer worldwide [1]. The addition of oxaliplatin to fluorouracil (FOLFOX) or capecitabine (CAPOX) has become a fundamental component of chemotherapeutic regi…
Adel Gabr, Ahmed A. S. Salem, Haisem Ahmed Samy, Shimaa Tmam, Anwar Mohammed Ali
Oxaliplatin and infusional fluorouracil/leucovorin or capecitabine ha s emerged as important options in the adjuvant and palliative treatment of colorectal cancer. Severe Oxaliplatin induced neurotoxicity may require chemotherapy dose reduction or cessation.…
Mohamed Serag, Mohamed Mahmoud, Ahmed Seleem, Mervat Elnagar
Aim of the study: To identify all clinico-pathological data, different treatment modalities and the different prognostic factors which affected the locoregional control (LC), disease-free survival (DFS), and overall survival (OS) of Type II endometrial cancer…
Sarp K. Keskin, Asif Yildirim, Cengiz Canakci, Ismail Ulus, Ramazan Gokhan Atis, Turhan Caskurlu
In the targeted therapy era, it is critical to know the certain points to start or discontinue chemotherapy for patients with castration resistant metastatic prostate cancer. The prognostic factors to determine this response are still not clear yet. We tried…
Alberto Olaya-Vargas, Martín Pérez-García, Nideshda Ramírez-Uribe, M. Angeles Del Campo-Martinez, Gerardo Lopez-Hernández, Montserrat Hernández-García, Jorge Amador-Zarco, Guadalupe Garcia-Vega, Yadira Melchor-Vidal, Marta Zapata-Tarres, Rocío Cárdenas-Cardos, Roberto Rivera-Luna
Total body irradiation (TBI) is conditioning regimen in children with acute lymphoblastic leukemia (ALL) with a very high risk of relapse or in those who have not achieved remission and have relapsed and subsequently received allogenic hematopoietic stem cell…
Adela Wu, Michael Lim
Glioblastoma (GBM) is the most common primary brain malignancy in adults and has a poor prognosis despite standard of care treatment. The mainstay of GBM treatment has relied on maximum surgical resection and chemotherapy and radiation. Cancer immunotherapy h…
Ashapurna Sarma, Vishal P. Sharma, Michael E. Geusz
Alterations of drug efficacy by the circadian clock are a concern when assessing drug therapies. Circadian rhythms persist in some cancer cells and are repressed in others. A better understanding of circadian activities generated within cancer cells could ind…
Hanan E. Shafik, Salem H. Alshemmary, Mohamed Ashour
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The most significant prognostic factors are tumor stage, histological grade and type, depth of myometrial invasion, lympho-vascular space or nodal involvement.…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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