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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Lorenzo Bruno, Lucia Barni, Gaia Masini, Sabrina Pacciani, Edvige Lucarelli, Antonella Masserelli, Daniela Tomcykova, Filippo Melli, Luca Boni, Giancarlo Freschi, Paolo Bechi
The aim of this study was to evaluate the accuracy of multiple detector computed tomography (MDCT) in the preoperative staging of gastric cancer, prospectively comparing CT findings with pathological findings at surgery, in a single-center study. A total of 1…
Stanislaw R. Burzynski, Tomasz J. Janicki, Gregory S. Burzynski, Sheldon Brookman
The most common and aggressive type of brain tumor is glioblastoma multiforme (GBM). The prognosis for GBM remains poor with a five-year survival rate between 1% and 2%. The prospects for patients with recurrent GBM (RGBM) are much worse, with the majority dy…
Cheryl Alecrim Santos, Gabriela Soares da Silva Brito, Silvana Aparecida Alves Corrêa de Noronha, Samuel Marcos Ribeiro de Noronha, Suma Imura Shimuta, Clovis Ryiuchi Nakaie, Ismael Dale Cotrim Guerreiro da Silva
Angiotensin-(1-7) [Ang-(1-7)] is a heptapeptide of the renin-angiotensin system with vasodilator and anti-proliferative properties. In the present study, we aim to investigate whether Ang-(1-7) induces apoptosis in breast cancer cells and whether the altered…
Drew Freilich, Eric Moskowitz, Nicholas Feuer, Muhammad Choudhury, John Phillips, Sensuke Konno
Chemotherapy is currently one of the most common therapeutic options for cancer patients despite the poor efficacy with considerable side effects. We then examined if D-fraction (DF), a bioactive mushroom extract, could potentiate (poor) anticancer effects of…
Caroline Brenner Larsen, Jan Lindebjerg, Rikke Fredslund Andersen, Niels Pallisgaard, Susanne Holck, Anders Jakobsen, Hans Jørgen Nielsen
Most colorectal cancers evolve through an adenoma-carcinoma sequence with mutations in the KRAS/BRAF pathway as an early event. Mutation analyses are usually performed on tissue samples, but during the last couple of years the same analysis in blood has been…
Shintaro Ishiyama
Purpose: In defining the biological effects of the 10 B( n , α ) 7 Li neutron capture reaction, we have previously developed a deterministic parsing model to determine the Compound Biological Effectiveness ( CBE ) factor in Borono-Phenyl-Alanine ( BPA )-media…
Paul H. Levine, Heather J. Hoffman, Audra MacNeil, Salman Hashmi, Sherry X. Yang, Stephen Hewitt, Kenneth L. van Golen, Sandra M. Swain
Background: We recently evaluated four laboratory assays, vascular endothelial growth factor D (VEGF-D), E-cadherin, lymphatic vessel density (LVD) measured by podoplanin, and intra-lymphatic tumor emboli (ILTE), which showed notable differences between infla…
Misty Gamble, Elizabeth Tocci, Jennifer A. DeSimone, 1 1
The treatment of advanced stage MF is especially challenging as single agent overall response rates are in the 35% range and chronic recurrence is the rule. The treatment of CTCL across all stages of disease is aimed at the goal of achieving and sustaining re…
Yan Wang, Bing Lian, Ying Dong, Ningju Wang, Wenjun Yang
The incidence of gastric cancer (GC) in young patients has showed a stable or even slightly increasing trend in recent years all over the world. Little is known about the clinicpathological features of young patients with GC in Ningxia region, located in the…
Ling Gao, Qinghua Yu, Fengsheng Li, Jiangbin Feng, Xue Lu, Qingjie Liu, Xu Su, 1 1
Radiotherapy is one of important approaches for pulmonary adenocarcinoma. However, many studies have shown that radiation can also enhance the ability of tumor cells metastasis, although the lung adenocarcinoma could be killed. The increased metastasis induce…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).