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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Hironaga Satake, Akihito Tsuji, Takeshi Kotake, Mikio Fujita
Objective: To evaluate the feasibility of S-1 and high-dose cisplatin short hydration regimens for outpatients with unresectable metastatic gastric cancer. Methods: Data for individual outpatients treated in our institution were retrospectively pooled to asse…
Jing Cai, You Zhang, Irina Vergalasova, Fan Zhang, W. Paul Segars, Fang-Fang Yin
Purpose: To develop and test an integrated simulation system based on the digital Extended Cardio Torso (XCAT) phantom for 4-dimensional (4D) radiation therapy of lung cancer. Methods: A computer program was developed to facilitate the characterization and im…
Michael Nacif, Olfat Shaker
Transforming growth factor- β (TGF- β ) superfamily is a key player in the regulation of a wide variety of physiological processes from development to pathogenesis. Since the discovery of the prototypic member, TGF- β , almost three decades ago, there have be…
Christina Thomas, Lakshmi Sreedharan Pillai, Lissy Krishnan
Curcumin (Curc) is well known for its anticancer activity, but its poor solubility in aqueous medium is a major concern for little therapeutic outcome. Therefore, the effort to improve its bioavailability is a major research interest. The current study aimed…
Ahmed El Bastawisy, Maha Yahia, Abdel Rahman M. Abdel Rahman, Rabab Gaafar
Background: Malignant pleural mesothelioma is a lethal disease and hence the strong need for identifying new prognostic factors. Methods: This is a retrospective study including all eligible patients with advanced malignant pleural mesothelioma (MPM) presenti…
Pierre Yves Marcy, Véronique Mari, Andréa Figl, Isabelle Ben-Taarit, Yves Fouché, Frédéric Peyrade, Philippe Follana, Cécile Michel, Emmanuel Chamorey
Rationale : Most cancer patients require a totally-implanted Central Venous Catheter (CVC) for their treatment. We develop and validate a French-language questionnaire dubbed QASICC (Questionnaire for Acceptance of and Satisfaction with Implanted Central Veno…
Annabelle Trojan, Lina M. Jay, Heliodor Kasprzak, Donald D. Anthony, Jerzy Trojan
The review article describes the criteria established for methodology of antisense anti IGF-I therapy of malignant tumors, particularly of glioblastoma. The cancer patients, after classical therapy of surgery, radiotherapy and chemotherapy, have undergone the…
Rachel M. Whynott, Nauman Khurshid, Seema Nayak, Kelly J. Manahan, John P. Geisler
Background: Diaphragm surgery is common with advanced ovarian malignancies. The purpose of this study is to determine associated factors with the need for drainage of pleural effusion after diaphragm surgery. Methods and Materials: A retrospective chart revie…
Yongzhuang Su
Since chemotherapy started in 1940s, chemosensitivity testing has been both a very attractive field and one fraught with potential pitfalls. Many methods were developed and brought initial promises, yet later ending in disappointment and were eliminated. For…
Yasuhiro Ebihara, Miwako Iwai, Ken Akashi, Takeshi Ito, Go Omura, Yuki Saito, Masafumi Yoshida, Mizuo Ando, Takahiro Asakage, Tatsuya Yamasoba, Yoshinori Murakami
Objective: Molecular targeting therapy has not been generally established in head and neck squamous cell carcinoma (HNSCC) except for cetuximab treatment for targeting epidermal growth factor receptor ( EGFR ). We analyzed alterations of the TP 53, KRAS 2, an…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
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