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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b…
Elisabetta Carraro, Mattia Roppolo, Sara Bonetta, Giorgio Gilli
Context: Physical exercise is a key component of treatment and management of people with Type 2 Diabetes, but the role of strategies and interventions to increase and promote physical activity is unclear. Objective: To conduct a systematic review of intervent…
François Djrolo, Thierry Adoukonou, Corine Houehanou, Josel D. Houinato, Dismand Houinato
An epidemic trend is observed in the evolution the epidemiology of diabetes mellitus worldwide. In a nationwide survey conducted in 2008, prevalence of diabetes was estimated to 2.6% in the hole Beninese population and to 4.6% in Borgou department representin…
Kazunori Takemoto, Wakana Doi, Ken Kataoka, Kohji Ishihara, Da-Hong Wang, Hitoshi Sugiyama, Noriyoshi Masuoka
Background: Catalase deficiency (acatalasemia) is sensitive to alloxan, and the administration to acatalasemic mice develops hyperglycemia under mild conditions. However, the mechanism is still poorly understood. Methods: Alloxan was used to induce the oxidat…
Yasuhiro Tanji, Suguru Yamaguchi, Yasushi Ishigaki, Hideki Katagiri, Yoshitomo Oka, Hisamitsu Ishihara
Wolfram syndrome, an autosomal recessive disorder associated with diabetes and optic atrophy, is caused by mutations in the WFS1 gene encoding wolframin, an endoplasmic reticulum membrane protein. Recent development of incretin-based drugs demonstrates promis…
R. Ramesh, N. AdhishwarKumaran, V. KuzhandaiVelu, R. Reeta, M. SathishBabu, G. Niranjan
Bilirubin has both antioxidant activity and cardioprotective potential. Decreased levels are associated with predicting CAD. Recent studies showed that bilirubin has inverse correlation with glycemic status. So in this we evaluated the role of Hepatobiliary f…
Jephthah O. Odiba, Mzwandile A. Mabhala
Background: Insulin therapy has been the mainstay in managing women with gestational diabetes mellitus (GDM), but some disadvantages of insulin have led to the use of glyburide, which is inexpensive in some countries, to manage GDM. However, there has been de…
Prosper Obunikem Uchechukwu Adogu, Henry Nnaemeka Chineke, Morris Uzoma Ewuzie, Okezie Oguamanam Enwere, Nonye Bibiana Egenti
Background: The rising prevalence of diabetes mellitus imposes great burden on health worldwide. The burden is enormous in terms of pressure on existing human and material health resources. Diabetes is insidious in onset and has many patterns of presentation…
Gaytán-Hernández Darío, Domínguez-Cortinas Gabriela, Mejía-Saavedra José de Jesús, Márquez-Mireles Leonardo Ernesto
Objective: To evaluate the morbidity due to diabetes mellitus type 2 within the State of San Luis Potosí, México, through a strong methodology, through which the multivariate relations were identified of the main social and environmental determiners in the di…
Yukihiro Bando, Kousuke Shima, Keiko Aoki, Hideo Kanehara, Azusa Hisada, Kazuhiro Okafuji, Daisyu Toya, Nobuyoshi Tanaka
Background: Treatment for postprandial glycemia using rapid-acting insulin analogues sometimes resulted in preprandial hypoglycemia or weight gain. Objective: This study evaluated the efficacy and safety of switching bolus insulin from insulin lispro (Lis) to…
Udaya M. Kabadi, Mary U. Kabadi, Sommany Weber, Aaron Bubolz, Edward Finnerty
Background: UKPDS suggested relentless deterioration of β cell function as a part of natural course of type 2 diabetes mellitus. However, the course was apparently not universal since many patients maintained glycemic goal (HbA1c < 7.0%) at 9 years while rece…
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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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