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Vaccines, immune-based therapies and antimicrobials followed from immunological mechanism through to clinical evidence.
Zhiwei Hu
Natural killer (NK) cells play an important role in innate immunity and in mediating antibody and Icon (an antibody-like factor VII/IgG1 Fc immunoconjugate, which, to our best knowledge, was the first therapeutic agent for dual targeting of both the tumor cel…
Jerry T. Thornthwaite, Hare Shah, Pashupati Shah, Henry Respess
The Natural Killer Cell (NKC) is the cell-mediated cornerstone of innate immunity. The purpose of this reviewis to give a historical perspective of the discovery of the Natural Killer Cell (NKC)and to apply the use of supplements in the enhancement of NKC in…
Suzannah M. Schmidt, Melissa J. Karau, Jayawant N. Mandrekar, James M. Steckelberg, Robin Patel
We determined whether telavancin is as active in experimental immunocompetent murine pneumococcal pneumonia as is vancomycin or ceftriaxone. Experimental murine pneumonia was established by intratracheal administration of Streptococcus pneumoniae. Four groups…
Adam Hasan, Magdalen Foo, Danesi Sadoh, Bret Jones
Chronic periodontitis (CP) is a chronic inflammatory condition which destroys the supporting tissues of teeth and increases in prevalence with age. Immune responses against heat shock proteins (HSP) can be cross-reactive among bacterial and human antigens. Th…
Hjalte List Larsen, Anders Elm Pedersen
Vaccination with tumor-antigen pulsed, monocyte-derived dendritic cells (DCs) has emerged as a promising strategy in cancer immunotherapy. The standard DC maturation cocktail consists of a combination of tumor necrosis factor-α (TNF-α)/interleukin (IL)-1β/IL-…
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The Journal of Immune Based Therapies, Vaccines and Antimicrobials covers the discovery, development, and clinical application of vaccines, immune-based therapies, and antimicrobial agents. It spans infectious disease, oncology, transplantation, allergy, and autoimmunity, and welcomes work on mechanism, formulation and delivery, and regulatory and clinical development. Every submission is assessed by at least two independent experts. All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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JIBTVA publishes work that runs from immunological mechanism through to clinical evidence. What follows applies to whichever stage your manuscript reports.